DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND2 and ND2

DIOPT Version :9

Sequence 1:	YP_003024027.1	Gene:	ND2 / 4536	HGNCID:	7456	Length:	347	Species:	Homo sapiens
Sequence 2:	YP_009047266.1	Gene:	ND2 / 19893529	FlyBaseID:	FBgn0013680	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	137/356 - (38%)
Similarity:	205/356 - (57%)	Gaps:	41/356 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     8 VIYSTI-FAGTLITALSSHWFFTWVGLEMNMLAFIPVLTKKMNPRSTEAAIKYFLTQATASMILL 71
            :::.|| ..|||||..|:.|...|:|||:|:|:|||:|:...|..||||::||||||..||.:||
  Fly     8 ILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQVLASTVLL 72

Human    72 ----MAILFNNMLSGQWTMTNTTNQ-YSSLMIMMAMAMKLGMAPFHFWVPEVTQGTPLTSGLLLL 131
                :.:|.||       |.|..|: ::|::||.|:.:|.|.||||||.|.:.:|....:.|:|:
  Fly    73 FSSILLMLKNN-------MNNEINESFTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLM 130

Human   132 TWQKLAPISIMYQISPSLNVSLLLTLS-ILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLP 195
            ||||:||:.::    ..||:..||.:| |||::.|:.||||||.|||::|:|||.|:|||::.|.
  Fly   131 TWQKIAPLMLI----SYLNIKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLM 191

Human   196 YNPNMTILNLTIYIILT------TTAFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTL----LS 250
            .:.::.::....|..|:      ...|.|.:||...:..:.|:          ::..||    ||
  Fly   192 ISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSK----------ILKFTLFMNFLS 246

Human   251 LGGLPPLTGFLPKWAIIEEFTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKW 315
            ||||||..||||||.:|::.|..|...:.|:|...||:.|:||||:.|| :..:....||..||.
  Fly   247 LGGLPPFLGFLPKWLVIQQLTLCNQYFMLTLMMMSTLITLFFYLRICYS-AFMMNYFENNWIMKM 310

Human   316 QFEHTKPTPF-LPTLIALTTLLLPISPFMLM 345
            .........: :.|..::..|.| ||.|..|
  Fly   311 NMNSINYNMYMIMTFFSIFGLFL-ISLFYFM 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND2	YP_003024027.1	ND2	1..346	CDD:177167	137/356 (38%)
ND2	YP_009047266.1	ND2	1..340	CDD:214442	133/349 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147871
Domainoid	1	1.000	191	1.000	Domainoid score	I3256
eggNOG	1	0.900	-	-		E1_COG1007
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3585
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46773
OrthoDB	1	1.010	-	-		D1153818at2759
OrthoFinder	1	1.000	-	-		FOG0002463
OrthoInspector	1	1.000	-	-		oto89890
orthoMCL	1	0.900	-	-		OOG6_102147
Panther	1	1.100	-	-	LDO	PTHR46552
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2690
SonicParanoid	1	1.000	-	-		X2194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800