DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and LRG1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_010041.2	Gene:	LRG1 / 851358	SGDID:	S000002399	Length:	1017	Species:	Saccharomyces cerevisiae

Alignment Length:	218	Identity:	46/218 - (21%)
Similarity:	71/218 - (32%)	Gaps:	58/218 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   616 RQLMSARP-----------CDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRE-------- 661
            |.|.:|.|           |..|:.|:.........|.......:|.:||.|..|::
Yeast     9 RSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFP 73

  Fly   662 ----------LLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFAC 716
                      ||....||.|...:             |..||..:.....| |.|..:...||:|
Yeast    74 YQVDKTSESILLCQYDYFRRHNLL-------------CHVCDTPLRGLYYT-AFGYRYDEEHFSC 124

  Fly   717 HECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYC-----GEAIGVDQGQMSHDGQHWHATDEC 776
            ..|....|.::..|...:.||.:.|...|::.|..|     .:.|...:|:..|   .||  .||
Yeast   125 TICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIH---CWH--PEC 184

  Fly   777 FSCN-----TCRCSLLGRAFLPR 794
            :..:     ......:|..:||:
Yeast   185 YGIHKYWHVNLAAETVGLQYLPK 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	1/1 (100%)
		LIM1_Prickle	624..682	CDD:188799	14/75 (19%)
		LIM2_Prickle	687..742	CDD:188802	14/54 (26%)
		LIM3_Prickle	747..805	CDD:188804	12/58 (21%)
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777	11/61 (18%)
		LIM	98..149	CDD:259829	14/51 (27%)
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	1	1.000