Protein Alignment pk and Tgfb1i1

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: XP_006230411.1
• Gene: Tgfb1i1 / 84574
• RGDID: 620173
• Length: 473
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 127/591 - (21%)
• Similarity: 181/591 - (30%)
• Gaps: 220/591 - (37%)

  Fly   256 PKQKQQRPVPPLPPPPANRVTQDQGTQPAAPQVPLQPLTAGDLQFLNLSLRQRSLPRSMKPFKDA 320
            ||::....:.| |||..::.....|....|         :||...|..::.:...|:|:.|
  Rat    36 PKERPPETLTP-PPPYGHQPQTGSGESSGA---------SGDKDHLYSTVCKPRSPKSVAP---- 86

  Fly   321 HDISFTFNELDTSAEPEVATGAAQ-----QESNEPISRTPLTQISYLQKIPT-LPRHFSPSGQG- 378
              ::..|    :|:...:..|..:     ||.|       .||.:...:|.: .|......|:|
  Rat    87 --VAPPF----SSSSGVLGNGLCELDRLLQELN-------ATQFNITDEIMSQFPSSKMAEGEGK 138

  Fly   379 --------LATPPALGSGGMGLPSSSSASALYAAQAAAGILPTSPLPLQRHQQYLPPHHQQHPGA 435
                    :.|.|:     ...|:.|..||..|.|....::  :.|...|.|.:||
  Rat   139 EDQSEDKSITTVPS-----STFPAPSKPSATSATQELDRLM--ASLSDFRVQNHLP--------- 187

  Fly   436 GMGPGPGSGAAAGPPLGPQYSP---GCSANPKYSNAQLPPPPHHHHQLSPALSTPSPPSLLHHPA 497
                      |:|||..|..||   ||                           ||||
  Rat   188 ----------ASGPPQPPAVSPTREGC---------------------------PSPP------- 208

  Fly   498 GGTSSASAHAPFLGGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVN 562
            |.|:..|... .||....|:.|:.                                    ||
  Rat   209 GQTNKGSLDT-MLGLLQSDLSRRG------------------------------------VP--- 233

  Fly   563 SPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDALGRGNVRQLMSARPCDGC 627
                                                    ||.|               ..|..|
  Rat   234 ----------------------------------------TQAK---------------GLCGSC 243

  Fly   628 DDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSAC 692
            :..|: |.:   .|.||  .:|||..|.|..|...|....:|.:||..:|...:.|...|||..|
  Rat   244 NKPIA-GQV---VTALG--RAWHPEHFLCRGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFC 302

  Fly   693 DEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIG 757
            ::.| ..:...|.|..||..||.|..|.:..|.:.:..|||:|||...|..:||..|..|...|
  Rat   303 NQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI- 365

  Fly   758 VDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYC---------SIACSKGEPPTPS 813
            :| ..:|.....||  .:||.|..|.....|.:|....|...|         |:..:.|.|.|..
  Rat   366 LD-NYISALSALWH--PDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQRGSLCATCGLPVTGR 427

  Fly   814 DSSGTG 819
            ..|..|
  Rat   428 CVSALG 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	5/94 (5%)
		LIM1_Prickle	624..682	CDD:188799	18/57 (32%)
		LIM2_Prickle	687..742	CDD:188802	20/54 (37%)
		LIM3_Prickle	747..805	CDD:188804	16/66 (24%)
Tgfb1i1	XP_006230411.1	Paxillin	<69..>118	CDD:281527	12/65 (18%)
		LIM1_Paxillin_like	240..292	CDD:259830	18/57 (32%)
		LIM2_Paxillin_like	299..350	CDD:188723	18/51 (35%)
		LIM3_Paxillin	358..410	CDD:188793	15/55 (27%)
		LIM4_Leupaxin	417..468	CDD:188796	5/17 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920