Protein Alignment pk and ZYX

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: NP_001010972.1
• Gene: ZYX / 7791
• HGNCID: 13200
• Length: 572
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 141/607 - (23%)
• Similarity: 217/607 - (35%)
• Gaps: 192/607 - (31%)

  Fly   241 EEESP-----EQEAPKPALPPKQKQQRPVPPLPPPPANRVTQDQGTQPAAPQVPLQPLTAGDLQF 300
            ||..|     |:..|.|. ||.:::..|..|:||||.                |.:.:::.||:.
Human   101 EESFPPAPLEEEIFPSPP-PPPEEEGGPEAPIPPPPQ----------------PREKVSSIDLEI 148

  Fly   301 LNLSLRQRSLPRSMKPFKDAHDISFTFNELDTSAEPEVATGAAQQESNEPISRTPLTQISYLQKI 365
            .:||.....:.:: .|||......:        ..|.|||..:.:.|.:
Human   149 DSLSSLLDDMTKN-DPFKARVSSGY--------VPPPVATPFSSKSSTK---------------- 188

  Fly   366 PTLPRHFSPSGQGLATPPALGSGGMGLPSSSSASALYAAQAAAGILPTSPLPLQRHQQY-LPPHH 429
                    |:..|.|..|...|     ||||..            ||..|.|.|...|: :.|..
Human   189 --------PAAGGTAPLPPWKS-----PSSSQP------------LPQVPAPAQSQTQFHVQPQP 228

  Fly   430 QQHPGAGM-----------------GPGPGSGAAAGP---PLGPQYSPGCSANPKYSNAQLPPPP 474
            |..|...:                 || |.|..|..|   |:.|:::|..|   |:|..
Human   229 QPKPQVQLHVQSQTQPVSLANTQPRGP-PASSPAPAPKFSPVTPKFTPVAS---KFSPG------ 283

  Fly   475 HHHHQLSPALSTPSPPSLLHHP---AGGTSSASAHAPFLGGPHMDMQRQSHSDDDSGCALEEYTW 536
                  :|..|...|...|.||   :.||          |.|.
Human   284 ------APGGSGSQPNQKLGHPEALSAGT----------GSPQ---------------------- 310

  Fly   537 VPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPP---HDNEVRYCHS---LTDEER 595
             ||.....|.|                  |:.||::..|.:||   :.|:||...:   ||.:|.
Human   311 -PPSFTYAQQR------------------EKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEV 356

  Fly   596 KELRLFSTQRKRDALGRGNVRQLMSARP-CDGCDDLISTGDIAVFATRLGPNASWHPACFACSVC 659
            :||...:.|..:|.  ....||.::... |..|...::....||.|  ||  ..:|.|||.|..|
Human   357 EELEQLTQQLMQDM--EHPQRQNVAVNELCGRCHQPLARAQPAVRA--LG--QLFHIACFTCHQC 415

  Fly   660 RELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLG 724
            .:.|....::..:|..||...:.:||: :|:.|.|.| .|....|.|:|:|.:.|.|..|.:.|.
Human   416 AQQLQGQQFYSLEGAPYCEGCYTDTLE-KCNTCGEPI-TDRMLRATGKAYHPHCFTCVVCARPLE 478

  Fly   725 GQRYIM-REGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQ------MSHDGQHWHATDECFSCNTC 782
            |..:|: :..:|:|:..:...:|..|..|.|.|..:.|:      ::.| :::|.  :|:.|..|
Human   479 GTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALD-KNFHM--KCYKCEDC 540

  Fly   783 RCSLLGRA----FLPRRGAIYC 800
            ...|...|    ..|..|.:.|
Human   541 GKPLSIEADDNGCFPLDGHVLC 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	21/100 (21%)
		LIM1_Prickle	624..682	CDD:188799	17/57 (30%)
		LIM2_Prickle	687..742	CDD:188802	17/55 (31%)
		LIM3_Prickle	747..805	CDD:188804	15/64 (23%)
ZYX	NP_001010972.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..351		80/383 (21%)
		PAT1	<201..>365	CDD:330585	54/247 (22%)
		LIM1_Zyxin	351..437	CDD:188735	26/91 (29%)
		LIM	444..503	CDD:295319	18/59 (31%)
		LIM3_Zyxin	504..570	CDD:188819	15/62 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810