DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pk and fblim1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001070771.1	Gene:	fblim1 / 768160	ZFINID:	ZDB-GENE-061013-662	Length:	292	Species:	Danio rerio

Alignment Length:	350	Identity:	82/350 - (23%)
Similarity:	119/350 - (34%)	Gaps:	95/350 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   461 ANPKYSNAQLPPPPHHHHQLSPALSTPSPPSLLHHPAGGTSSASAHAPFLGGPHMDMQRQSHSDD 525
            |:|  |.|.:.|..|..|  |||.:..:.|:                    ||
Zfish    19 ASP--SRATVTPTAHGQH--SPARAQNTAPT--------------------GP------------ 47

  Fly   526 DSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSL 590
               |.....:.|||..|         .:.|.|......|.|...|             :|...|.
Zfish    48 ---CRTHVVSGVPPAPR---------DLCDPKRDLSGGPAEDGAV-------------LRSAPSA 87

  Fly   591 TDEERKELRLFSTQRKRDALGRGNVRQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFA 655
            ..:|:::                :......:..|..|...:|..:.|:.|.    |..:|..||.
Zfish    88 GGQEKQQ----------------SDTHTHCSDVCGFCRKQVSPCESAIVAL----NRCYHSGCFQ 132

  Fly   656 CSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECD 720
            |..|...|....|:.|.|...|...|..:|:| |.||.::| .|....|..||:|...|.|..|.
Zfish   133 CRQCCAPLAGRQYYSRSGLPLCEACHQASLEP-CWACGDVI-KDHVIRALERAYHPPCFVCTTCR 195

  Fly   721 KQLGGQRYIMRE-GKPYCLHCFDAMFAEYCDYCGEAI-----GVDQGQMSHDGQHWHATDECFSC 779
            :.:|.||:...| |:.|||..:...:|..|..||..|     |.|...:...|:.:|  ::|:.|
Zfish   196 QPIGEQRFAQGEVGEVYCLQDYYRKYAPQCGVCGLMIIPRDDGTDSFTVECLGRSYH--EDCYRC 258

  Fly   780 NTCRCSLL----GRAFLPRRGAIYC 800
            ..|...|.    .|...|..|.:.|
Zfish   259 QVCAVLLSPEPDERGCHPLDGQMLC 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	13/94 (14%)
		LIM1_Prickle	624..682	CDD:188799	16/57 (28%)
		LIM2_Prickle	687..742	CDD:188802	21/55 (38%)
		LIM3_Prickle	747..805	CDD:188804	15/62 (24%)
fblim1	NP_001070771.1	LIM	<100..158	CDD:295319	16/61 (26%)
		LIM	165..217	CDD:295319	20/52 (38%)
		LIM	225..287	CDD:295319	15/60 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810