DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Fhl2

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_113865.1	Gene:	Fhl2 / 63839	RGDID:	61963	Length:	279	Species:	Rattus norvegicus

Alignment Length:	187	Identity:	59/187 - (31%)
Similarity:	86/187 - (45%)	Gaps:	14/187 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 CDGCDDLISTGDIAVFATRL--GPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLK 686
            |..|...|..|      ||.  ...:|||..||.|..|::.:....:..::.:.:|...:.:...
  Rat   101 CQECKKTIMPG------TRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYA 159

  Fly   687 PRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDY 751
            .:|..|.:.|.....|..: :.||...|.|..|.|||.|||:..|:..||||.||..::|:.|..
  Rat   160 LQCVQCKKPITTGGVTYRD-QPWHRECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAG 223

  Fly   752 CGEAIGVDQG--QMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSK 806
            |...|....|  .:|.:.:.||  ::||:|..|..||:||.||..|..|.|. .|.|
  Rat   224 CTNPISGLGGTKYISFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILCP-DCGK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	14/59 (24%)
		LIM2_Prickle	687..742	CDD:188802	21/54 (39%)
		LIM3_Prickle	747..805	CDD:188804	20/59 (34%)
Fhl2	NP_113865.1	LIM	<5..33	CDD:413332
		LIM	36..97	CDD:413332
		LIM2_FHL2	101..157	CDD:188810	14/61 (23%)
		LIM	162..218	CDD:413332	22/56 (39%)
		LIM4_FHL2	221..278	CDD:188817	22/60 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810