Protein Alignment pk and LIMS2

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: NP_060450.2
• Gene: LIMS2 / 55679
• HGNCID: 16084
• Length: 365
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 72/262 - (27%)
• Similarity: 103/262 - (39%)
• Gaps: 55/262 - (20%)

  Fly   554 PDDKVPYVNSPGEQYR-----VRQLLHQLPP---HDNEVR-YCHSLTDEERKELRLFSTQRKRDA 609
            |.:::  |||.||.|.     ..|.....|.   ::.|.| ||      |.....||:
Human    48 PAERI--VNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC------EHDFQMLFA------- 97

  Fly   610 LGRGNVRQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGR 674
                         ||.|     |.|:..:.......|.:|||.||.|.:|...|.||.:....||
Human    98 -------------PCCG-----SCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGR 144

  Fly   675 MYC----GRHHAETL-KPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGK 734
            ..|    .|..|:.| |..|..| .:::.::.......|:|.:||.|..|.|:|..:...:: |:
Human   145 HLCRPCHNREKAKGLGKYICQRC-HLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GE 207

  Fly   735 PYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHD-GQHWHATDECFSCNTCRCSLLGRAFLPRRGAI 798
            .|||.|.|.|....|..|...|   :|::.:. |:.||.  |.|.|..|....||.....::|..
Human   208 LYCLPCHDKMGVPICGACRRPI---EGRVVNALGKQWHV--EHFVCAKCEKPFLGHRHYEKKGLA 267

  Fly   799 YC 800
            ||
Human   268 YC 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	16/72 (22%)
		LIM1_Prickle	624..682	CDD:188799	19/61 (31%)
		LIM2_Prickle	687..742	CDD:188802	15/54 (28%)
		LIM3_Prickle	747..805	CDD:188804	16/55 (29%)
LIMS2	NP_060450.2	LIM1_PINCH	39..97	CDD:188717	15/56 (27%)
		LIM2_PINCH	100..151	CDD:188718	17/55 (31%)
		LIM3_PINCH	164..214	CDD:188719	14/51 (27%)
		LIM4_PINCH	220..273	CDD:188720	16/55 (29%)
		LIM5_PINCH	281..334	CDD:188721

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820