DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and tes

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001004961.1	Gene:	tes / 448383	XenbaseID:	XB-GENE-1015357	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	119/308 - (38%)
Similarity:	164/308 - (53%)	Gaps:	35/308 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   534 YTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKEL 598
            |.|.||.......|.|...||.||.|...|.|.|||.:||..|||.||.:...||.|:..|.|::
Frog   111 YEWAPPVQNQALARRYMELIPKDKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPNEVKQM 175

  Fly   599 RLFSTQRKRDALGRGNVR-----------------------------------QLMSARPCDGCD 628
            ..|..:.|.:.||.|:|:                                   |..|...|..|.
Frog   176 EQFVKKYKNEVLGVGDVKLPKEVEAQACGAGRSTNGSLSTLTTVKGTEDKVAAQKESTYYCFRCK 240

  Fly   629 DLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACD 693
            :.:..||.||:|.|.|.:..|||:||.|..|.|||||:|||.::|::|||||:.::.||||:.||
Frog   241 ENMREGDPAVYAERAGYDKLWHPSCFVCFTCNELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCD 305

  Fly   694 EIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGV 758
            |:|.::|.|:|||..||:.||.|.:||..|.|:.|:|...||.|..|:....|..|..|..||..
Frog   306 ELIFSNEYTQAEGLNWHLKHFCCFDCDCVLAGEIYVMVNDKPVCKLCYVKNHAVSCQGCHNAIDP 370

  Fly   759 DQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSK 806
            :..::|::|.||||..|||.|:.|...|:|:.|:|.:|.::||:.|.|
Frog   371 EVQRVSYNGFHWHAAPECFICSCCSKCLIGQKFMPIQGMVFCSVDCKK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	34/118 (29%)
		LIM1_Prickle	624..682	CDD:188799	30/57 (53%)
		LIM2_Prickle	687..742	CDD:188802	27/54 (50%)
		LIM3_Prickle	747..805	CDD:188804	22/57 (39%)
tes	NP_001004961.1	PET_testin	109..195	CDD:193604	34/83 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..165		13/29 (45%)
		LIM1_Testin	236..293	CDD:188797	29/56 (52%)
		LIM2_Testin	299..354	CDD:188800	27/54 (50%)
		LIM3_Testin	361..419	CDD:188803	24/58 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920