DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and fhl5

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001004112.1	Gene:	fhl5 / 445475	ZFINID:	ZDB-GENE-040822-3	Length:	280	Species:	Danio rerio

Alignment Length:	156	Identity:	55/156 - (35%)
Similarity:	80/156 - (51%)	Gaps:	5/156 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   648 SWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMN 712
            |||..||.|..|::.:....:..:|...:|.....:....:|.||.:.|.....|..: :.||..
Zfish   122 SWHETCFLCQRCQQPIGTKSFIPKDNNYFCVPCFEKQFAYQCCACKKAITTGGVTYHD-KPWHRE 185

  Fly   713 HFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQG--QMSHDGQHWHATDE 775
            .|.|..|.:||.|||:..||..||||.||..::|:.|..|.:||....|  .:|.:.:.||:  |
Zfish   186 CFTCIGCKRQLAGQRFTSRENYPYCLDCFSNLYAKKCVGCTKAITSLAGAKYISFEERQWHS--E 248

  Fly   776 CFSCNTCRCSLLGRAFLPRRGAIYCS 801
            ||:|..|..||:||.||.:|..|.|:
Zfish   249 CFTCMQCSVSLVGRGFLTQRDDILCT 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	9/33 (27%)
		LIM2_Prickle	687..742	CDD:188802	22/54 (41%)
		LIM3_Prickle	747..805	CDD:188804	22/57 (39%)
fhl5	NP_001004112.1	LIM	<6..34	CDD:295319
		LIM1_FHL	37..95	CDD:188729
		LIM	102..158	CDD:295319	9/35 (26%)
		LIM3_FHL	163..214	CDD:188732	21/51 (41%)
		LIM4_FHL	222..277	CDD:188733	22/55 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810