DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and fhl2a

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001003732.1	Gene:	fhl2a / 445277	ZFINID:	ZDB-GENE-040808-49	Length:	279	Species:	Danio rerio

Alignment Length:	161	Identity:	53/161 - (32%)
Similarity:	79/161 - (49%)	Gaps:	6/161 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   648 SWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMN 712
            |||..||.|..|::.:....:..:|...||...:.:....:|..|.:.|.....|..: :.||.:
Zfish   121 SWHETCFTCQRCQQPIGTKSFIPKDNHNYCVPCYEKQFAMQCVHCKKPITTGGVTYHD-QPWHKD 184

  Fly   713 HFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQ--MSHDGQHWHATDE 775
            .|.|..|.:||.|||:..|:...|||:||..::|:.|..|...|....|.  :|.:.:.||  ::
Zfish   185 CFLCTGCKQQLSGQRFTSRDDFAYCLNCFCNLYAKKCASCTSPISGLGGSKYISFEERQWH--ND 247

  Fly   776 CFSCNTCRCSLLGRAFLPRRGAIYCSIACSK 806
            ||:|..|..||:||.||..|..|.|. .|.|
Zfish   248 CFNCKKCSVSLVGRGFLTDRDDILCP-ECGK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	10/33 (30%)
		LIM2_Prickle	687..742	CDD:188802	19/54 (35%)
		LIM3_Prickle	747..805	CDD:188804	20/59 (34%)
fhl2a	NP_001003732.1	LIM	<7..33	CDD:295319
		LIM1_FHL2	36..97	CDD:188806
		LIM2_FHL2	101..157	CDD:188810	10/35 (29%)
		LIM3_Fhl2	162..218	CDD:188815	20/56 (36%)
		LIM	221..278	CDD:295319	22/60 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810