DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and lmcd1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_957364.2	Gene:	lmcd1 / 394045	ZFINID:	ZDB-GENE-040426-1067	Length:	342	Species:	Danio rerio

Alignment Length:	227	Identity:	79/227 - (34%)
Similarity:	111/227 - (48%)	Gaps:	37/227 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   534 YTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKEL 598
            |.|.|.||......||.|.:|:::.|...:.|..||.:||..|||.:|::..|||||::.|.|.:
Zfish   104 YDWAPTGLTQKLAMLYMSLLPEERRPVAGTEGSLYRHKQLTRQLPAYDHDPAYCHSLSEAELKVM 168

  Fly   599 RLFSTQRKRDALGRGNV------------RQLMSARP------------------------CDGC 627
            ..|....|.::||.|.|            .::...:|                        |.||
Zfish   169 AQFVKSYKEESLGVGEVALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIESPVSNETEYYCSGC 233

  Fly   628 DDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSAC 692
            ..|.:..:..|:|.|.|....||||||.|..|.|.|||||||.::|.:.||||:.::::|||..|
Zfish   234 GQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCGRHYCQSIRPRCLGC 298

  Fly   693 DEIILADE-CTEAEGRAWHMNHFACHECDKQL 723
            ||:|.:|. ..||.|..||..||.|..|.:.:
Zfish   299 DELIFSDMLLQEASGHVWHKEHFCCWLCGQDI 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	32/95 (34%)
		LIM1_Prickle	624..682	CDD:188799	29/57 (51%)
		LIM2_Prickle	687..742	CDD:188802	17/38 (45%)
		LIM3_Prickle	747..805	CDD:188804
lmcd1	NP_957364.2	PET_testin	102..189	CDD:193604	32/84 (38%)
		LIM1_Testin_like	230..287	CDD:188726	28/56 (50%)
		LIM	293..>326	CDD:295319	16/32 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820