DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and fhl1b

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_954687.1	Gene:	fhl1b / 387528	ZFINID:	ZDB-GENE-031219-1	Length:	280	Species:	Danio rerio

Alignment Length:	187	Identity:	59/187 - (31%)
Similarity:	86/187 - (45%)	Gaps:	10/187 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 ARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETL 685
            |..|..|...|||....:.    .....||..||.|:.|.:.|....:..:|.|:.||...:...
Zfish    37 ANTCTECRRTISTDSKELH----HKGKYWHSDCFRCAKCYKNLAKESFTSKDDRILCGTCSSRED 97

  Fly   686 KPRCSACDEIIL-ADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYC 749
            .|||..|.:.|| ..|..|.:|.:||...|.|::|.|.:|.:.:|.:....||..|.:..||:.|
Zfish    98 APRCHGCYKPILPGTENVEYKGNSWHDECFKCYQCQKPIGNKSFITKNNNVYCSPCHEKKFAKQC 162

  Fly   750 DYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSK 806
            ..|.:.|  ..|.:::..|.||:  |||.|::||..|.|..|......:|| :.|.|
Zfish   163 ACCKKPI--TTGGVNYQDQPWHS--ECFVCSSCRKPLAGTRFTSHEEKVYC-VDCYK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	16/57 (28%)
		LIM2_Prickle	687..742	CDD:188802	20/55 (36%)
		LIM3_Prickle	747..805	CDD:188804	18/57 (32%)
fhl1b	NP_954687.1	LIM1_FHL1	40..93	CDD:188730	16/56 (29%)
		LIM2_FHL1	101..158	CDD:188808	18/56 (32%)
		LIM3_FHL1	162..214	CDD:188813	19/56 (34%)
		LIM4_FHL1	217..280	CDD:188734
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810