DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pk and Fhl4

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001013190.2	Gene:	Fhl4 / 314678	RGDID:	1308978	Length:	280	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	55/197 - (27%)
Similarity:	85/197 - (43%)	Gaps:	33/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 CDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPR 688
            |.||...|..|:.:|..    ....||..||.||.|:|::....:|.:|...|
  Rat   100 CKGCLKDIKQGEQSVEY----KGTIWHKDCFVCSNCKEVIGTKTFFPKDEGFY------------ 148

  Fly   689 CSACDEIILADECTEA-----------EGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFD 742
            |.||.:|:....|.:.           :.:.||...|.|..|.|:|..||:.:.:.|.:|:.|:.
  Rat   149 CVACYDILFTKYCVKCNKPITSGGVSYQDQPWHSECFVCVNCSKELSEQRFTVMDDKIFCVDCYK 213

  Fly   743 AMFAEYCDYCGEAI-GVDQGQ--MSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIAC 804
            ...|:.|..|...| |..:|.  ::|:...||  |.||:|..|..:|..:.|:..:..|||. .|
  Rat   214 NFIAKKCAGCKNPITGFGKGSNVVTHETNSWH--DYCFNCKACSVNLANKHFVFHQEQIYCP-DC 275

  Fly   805 SK 806
            :|
  Rat   276 AK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	17/57 (30%)
		LIM2_Prickle	687..742	CDD:188802	17/65 (26%)
		LIM3_Prickle	747..805	CDD:188804	18/60 (30%)
Fhl4	NP_001013190.2	LIM	39..91	CDD:413332
		LIM	100..157	CDD:413332	21/72 (29%)
		LIM	161..213	CDD:413332	13/51 (25%)
		LIM	216..279	CDD:413332	21/65 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910