DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Fhl3

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001101449.1	Gene:	Fhl3 / 313582	RGDID:	1307180	Length:	288	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	74/271 - (27%)
Similarity:	105/271 - (38%)	Gaps:	64/271 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   576 QLPPHDN-----EVRYCH-----------SLTDE----ERKEL-------RLFSTQRKRDALGRG 613
            ||..||:     |.|:.|           ||.||    :..||       ..||:|
  Rat    45 QLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQ--------- 100

  Fly   614 NVRQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCG 678
                      |..|.:.:..|...:   ..| ..:||..||.||.|.:.|....:....|..||.
  Rat   101 ----------CSACGETVMPGSRKL---EYG-GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCV 151

  Fly   679 RHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDA 743
            ..:.....|||:.|.:.:.....|..: :.||.....|..|...|.||::..|:..|||:.||..
  Rat   152 PCYENKFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDDDPYCVACFGE 215

  Fly   744 MFAEYCDYC---------GEAIGVDQGQ-MSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAI 798
            :||..|..|         .|..|:..|: :|.:.:|||  ..||||..|..||:|:.|:|....:
  Rat   216 LFAPKCSSCKRPITGGSGSEGAGLGGGKYVSFEDRHWH--HSCFSCARCSTSLVGQGFVPDGDQV 278

  Fly   799 YCSIACSKGEP 809
            .|. .||:..|
  Rat   279 LCQ-GCSQAGP 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	16/68 (24%)
		LIM1_Prickle	624..682	CDD:188799	15/57 (26%)
		LIM2_Prickle	687..742	CDD:188802	17/54 (31%)
		LIM3_Prickle	747..805	CDD:188804	20/67 (30%)
Fhl3	NP_001101449.1	LIM	<5..33	CDD:413332
		LIM1_FHL3	36..94	CDD:188807	13/48 (27%)
		LIM2_FHL3	98..155	CDD:188811	17/79 (22%)
		LIM3_FHL	162..213	CDD:188732	14/51 (27%)
		LIM	221..284	CDD:413332	20/65 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810