Protein Alignment pk and PRICKLE4

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: NP_037529.3
• Gene: PRICKLE4 / 29964
• HGNCID: 16805
• Length: 384
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 134/413 - (32%)
• Similarity: 183/413 - (44%)
• Gaps: 103/413 - (24%)

  Fly   477 HHQLSPALSTPSPPSLLHHPAGGTSSASAHAPFLGGPHMDMQRQSHSDDDSGCALEEYTWVPPGL 541
            |.:.||....|.||:       .:.|.|.|.|  |....|...|.                |..|
Human    10 HQEDSPKPQDPGPPA-------NSDSDSGHLP--GEDPEDTHAQG----------------PAVL 49

  Fly   542 RPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRK 606
            ....:.|..:|.|       |..|    ::.||.||||.|.:.|||.:|.:|||.||:||..:||
Human    50 SLGSLCLDTNQAP-------NWTG----LQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRK 103

  Fly   607 RDALGRGNVRQL---MSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIY 668
            ::|||:|..|.:   :....|:.|.:|:..|:..|||.|.|....||..||||..|.:.|::|||
Human   104 QEALGQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIY 168

  Fly   669 FHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREG 733
            |:.||::||||||||.|:|||.|||::|.:..||||||:.||.|||.|.:|...|||.||.:..|
Human   169 FYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGG 233

  Fly   734 KPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAI 798
            .|.|..||                  :.:.|..|..|..            :|.|:|||...|
Human   234 SPCCPSCF------------------ENRYSDAGSSWAG------------ALEGQAFLGETG-- 266

  Fly   799 YCSIACSKGEPPTPSDSS-----------GTGMYT----TPTPPTQRVRPHPQAPLP-----ARI 843
               :..::|...|..:|:           |:.:.|    ..:.|.|..||..:|..|     .|:
Human   267 ---LDRTEGRDQTSVNSATLSRTLLAAAGGSSLQTQRGLPGSSPQQENRPGDKAEAPKGQEQCRL 328

  Fly   844 ---------PSSHASSSPPMSPQ 857
                     |.|..|||....|:
Human   329 ETIRDPKDTPFSTCSSSSDSEPE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	32/94 (34%)
		LIM1_Prickle	624..682	CDD:188799	28/57 (49%)
		LIM2_Prickle	687..742	CDD:188802	29/54 (54%)
		LIM3_Prickle	747..805	CDD:188804	9/57 (16%)
PRICKLE4	NP_037529.3	PET_OEBT	1..116	CDD:193603	45/141 (32%)
		LIM1_Testin_like	124..181	CDD:188726	27/56 (48%)
		LIM2_Testin_like	187..242	CDD:188727	30/72 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770