DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Fhl1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	XP_006257733.1	Gene:	Fhl1 / 25177	RGDID:	2615	Length:	339	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	64/224 - (28%)
Similarity:	95/224 - (42%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   646 NASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILA-DECTEAEGRAW 709
            |..||..||.|:.|...|....:..:||::.|.:.......|||..|.:.|:| |:..|.:|..|
  Rat    74 NRYWHDTCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTIW 138

  Fly   710 HMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATD 774
            |.:.|.|..|.:.:|...:..:....||:.|.:..||::|..|.:||  ..|.:::..|.|||
  Rat   139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHA-- 199

  Fly   775 ECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKG----------EPPTPSDSSGTGMYTTPTPPTQ 829
            |||.|.||...|.|:.|.......|| :.|.|.          .|.|     |....:..:.|..
  Rat   200 ECFVCVTCSKKLAGQRFTAVEDQYYC-VDCYKNFVAKKCAGCKNPIT-----GKRTVSRVSHPVS 258

  Fly   830 RVRPHP-----QAPLPARIPSSHASSSPP 853
            :.|..|     :.|| ...||::.....|
  Rat   259 KARKSPVCHGKRLPL-TLFPSANLRGRHP 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	11/35 (31%)
		LIM2_Prickle	687..742	CDD:188802	18/55 (33%)
		LIM3_Prickle	747..805	CDD:188804	20/57 (35%)
Fhl1	XP_006257733.1	LIM	<21..49	CDD:351770
		LIM1_FHL1	56..109	CDD:188730	11/34 (32%)
		LIM2_FHL1	117..174	CDD:188808	16/56 (29%)
		LIM3_FHL1	178..230	CDD:188813	21/56 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810