Protein Alignment pk and prkl-1

DIOPT Version :10

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: NP_741435.2
• Gene: prkl-1 / 177463
• WormBaseID: WBGene00022727
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 176/517 - (34%)
• Similarity: 239/517 - (46%)
• Gaps: 97/517 - (18%)

  Fly   490 PSLL--HHPAGGTSSAS-------AHAPFLGGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQ 545
            |.|:  ....||.|.||       ||            |.|.|||||||||:||.|||.||:|:.
 Worm    18 PQLISSRRAQGGLSPASRIRIAADAH------------RHSTSDDDSGCALDEYAWVPSGLKPNM 70

  Fly   546 VRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDAL 610
            |..||:.:|::|||::.|.||::|.||..:||||.|::||||..|..||...||:|...||.:.|
 Worm    71 VHAYFACLPENKVPFIGSAGEKWRQRQSRYQLPPQDSDVRYCEDLNAEEADTLRMFERTRKTECL 135

  Fly   611 GRGNVRQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRM 675
            |.|.|:.......|:.|...:..|:|:|.|.|.|..  :||:||.|..|..||||||||..|.::
 Worm   136 GSGVVQYAPFDTKCEKCPKRLEEGEISVMAARTGKR--YHPSCFRCQTCDVLLVDLIYFAHDNQI 198

  Fly   676 YCGRHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHC 740
            ||||||||.:||||:.|||:|..|||.|||||:||.:||.|.:|:..|..|:|:.|..||.||.|
 Worm   199 YCGRHHAEQVKPRCAKCDEVIFGDECLEAEGRSWHFHHFQCAQCNDVLADQKYMQRANKPVCLKC 263

  Fly   741 FDAMFAEY-CDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIAC 804
            |.:..:.: |..|..:...|...||....||||:.|||.|..|..:|||..:.....:::|....
 Worm   264 FHSSSSTFSCTTCRLSFSSDTPHMSQGDLHWHASAECFCCCVCSKNLLGVKYSRVGESLFCGYQT 328

  Fly   805 SKGE------------PPTPSDSSGTGMYTTPTPP----------------------------TQ 829
            ..||            |........|.:...|..|                            .|
 Worm   329 CGGEDEELLDEDRLGSPHRKVTQKSTKVVRIPASPRVAPRHPHVIQQNLTTTMTIQKPSVVIQNQ 393

  Fly   830 RVRPHPQAPLPARIPSSH---------ASSSP----------PMSPQQQQQHQATFNQAMYQMQS 875
            |.:|..:||.|.  ||.:         :::||          |.||.....:..|.|..:.....
 Worm   394 RPKPPQRAPPPP--PSENIYETVLPCSSNNSPNFDKKYSHELPTSPNHHNYYSKTPNNLLTGYPE 456

  Fly   876 QQMEAAGGLVDQSKSYAASDSDAGVVKDLEHGGHMGGGDLTDFSGGRASSTSQNLSPLNSPG 937
                     :|...:.::||||.   :.|.....|....|:......:|..|:...|:...|
 Worm   457 ---------MDGYSTSSSSDSDD---EQLYISNIMAAASLSRVPAKSSSRKSKKNEPMMMSG 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	51/94 (54%)
		LIM1_Prickle	624..682	CDD:188799	28/57 (49%)
		LIM2_Prickle	687..742	CDD:188802	30/54 (56%)
		LIM3_Prickle	747..805	CDD:188804	18/58 (31%)
prkl-1	NP_741435.2	PET_Prickle	48..144	CDD:193602	51/95 (54%)
		LIM1_Testin_like	149..204	CDD:188726	27/56 (48%)
		LIM2_Testin_like	210..262	CDD:188727	28/51 (55%)
		LIM	283..324	CDD:413332	15/40 (38%)