DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Y1A5A.1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_497801.1	Gene:	Y1A5A.1 / 175515	WormBaseID:	WBGene00012379	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	49/184 - (26%)
Similarity:	73/184 - (39%)	Gaps:	24/184 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   561 VNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEERKEL----RLFSTQRKRDALGRGNVRQLMSA 621
            :.|....|.:..|...:|.:..::..|...   |.|.:    ..|:.:|...::.|
Worm    12 IMSVNPSYPLPLLCQYIPRYHPQMPTCPLF---ESKSIITPVFYFNCKRMDRSIDR--------- 64

  Fly   622 RPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLK 686
            |.|..|..  |.|..|:.|.    |..|||..|.||.|:. .:...:...|...||.:..|:...
Worm    65 RLCGHCHQ--SIGSEALVAM----NRLWHPDHFTCSSCKR-PIKQTFQAADNHAYCVQCFAQKYN 122

  Fly   687 PRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHC 740
            |:|:.|.| .|.|.|..|..|.||...|.|..|::.|....:.:.:.|||.|.|
Worm   123 PKCAGCME-TLVDTCLLALDRHWHPRCFTCSSCNRPLPNGEFYLVDDKPYDLDC 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	10/60 (17%)
		LIM1_Prickle	624..682	CDD:188799	17/57 (30%)
		LIM2_Prickle	687..742	CDD:188802	20/54 (37%)
		LIM3_Prickle	747..805	CDD:188804
Y1A5A.1	NP_497801.1	LIM	67..117	CDD:295319	17/56 (30%)
Y1A5A.1	NP_497801.1	LIM_DA1	125..176	CDD:188782	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920