DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Fhl4

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_034344.2	Gene:	Fhl4 / 14202	MGIID:	1338765	Length:	279	Species:	Mus musculus

Alignment Length:	159	Identity:	50/159 - (31%)
Similarity:	75/159 - (47%)	Gaps:	6/159 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   649 WHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSAC-DEIILADECTEAEGRAWHMN 712
            ||..||.||.|.:||....:...|..:.|.:.......|:|..| .:|...|...|.:|..||.|
Mouse    60 WHNTCFKCSKCSQLLATETFVAWDKNILCNKCATRVTFPKCKGCLKDIEEGDHNVEYKGSIWHKN 124

  Fly   713 HFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATDECF 777
            .|.|..|...:|.:.:..::...||:.|:||:|.::|..|.:.|  ..|.:|:..|.||:  |||
Mouse   125 CFVCTNCKDIIGTKNFFPKDEGFYCVTCYDALFTKHCMKCKKPI--TSGGVSYQDQPWHS--ECF 185

  Fly   778 SCNTCRCSLLGRAFLPRRGAIYCSIACSK 806
            .|.:|...|.|:.|.......:| :.|.|
Mouse   186 VCVSCSKELSGQRFTAMDDQYFC-VDCYK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	11/32 (34%)
		LIM2_Prickle	687..742	CDD:188802	17/55 (31%)
		LIM3_Prickle	747..805	CDD:188804	17/57 (30%)
Fhl4	NP_034344.2	LIM	<4..32	CDD:295319
		LIM	39..92	CDD:295319	11/31 (35%)
		LIM2_FHL1	100..157	CDD:188808	18/56 (32%)
		LIM3_FHL1	161..213	CDD:188813	18/56 (32%)
		LIM4_FHL1	216..279	CDD:188734
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810