DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and Fhl1

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	XP_006527864.1	Gene:	Fhl1 / 14199	MGIID:	1298387	Length:	339	Species:	Mus musculus

Alignment Length:	249	Identity:	70/249 - (28%)
Similarity:	101/249 - (40%)	Gaps:	31/249 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 ARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETL 685
            |..|..|...||.....|..    .|..||..||.|:.|...|....:..:||::.|.:......
Mouse    53 ANTCVDCRKPISADAKEVHY----KNRYWHDNCFRCAKCLHPLASETFVSKDGKILCNKCATRED 113

  Fly   686 KPRCSACDEIILA-DECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYC 749
            .|||..|.:.|:| |:..|.:|..||.:.|.|..|.:.:|...:..:....||:.|.:..||::|
Mouse   114 SPRCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHC 178

  Fly   750 DYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKG------- 807
            ..|.:||  ..|.:::..|.|||  |||.|.||...|.|:.|.......|| :.|.|.
Mouse   179 VKCNKAI--TSGGITYQDQPWHA--ECFVCVTCSKKLAGQRFTAVEDQYYC-VDCYKNFVAKKCA 238

  Fly   808 ---EPPTPSDSSGTGMYTTPTPPTQRVRPHP-----QAPLPARIPSSHASSSPP 853
               .|.|     |....:..:.|..:.|..|     :.|| ...||::.....|
Mouse   239 GCKNPIT-----GKRTVSRVSHPVSKARKSPVCHGKRLPL-TLFPSANLRGRHP 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	16/57 (28%)
		LIM2_Prickle	687..742	CDD:188802	18/55 (33%)
		LIM3_Prickle	747..805	CDD:188804	20/57 (35%)
Fhl1	XP_006527864.1	LIM	<21..49	CDD:351770
		LIM1_FHL1	56..109	CDD:188730	16/56 (29%)
		LIM2_FHL1	117..174	CDD:188808	16/56 (29%)
		LIM3_FHL1	178..230	CDD:188813	21/56 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810