Protein Alignment pk and Lmpt

DIOPT Version :10

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: XP_061499123.1
• Gene: Lmpt / 1276101
• VectorBaseID: AGAMI1_008000
• Length: 1083
• Species: Anopheles gambiae
• Alignment Length: 1116
• Identity: 227/1116 - (20%)
• Similarity: 344/1116 - (30%)
• Gaps: 350/1116 - (31%)

  Fly   114 DADDGIDLGD-HSSTPKGGATTAGRPLFPHSSSP----RRSKKLLRSLRAHVRGEKLPKNDTTTA 173
            ||...|.|.: |.|  .||.....||    |||.    ||...|.||::         :...|:.
Mosquito   179 DAVPQIVLNEPHDS--GGGGADEPRP----SSSKFRPIRRDDGLRRSVK---------RRSVTSV 228

  Fly   174 NESSEVTQRNARVTVLDDPFLFGIDADHLGDLVVRGKRYSTLDATENMARFYAEQEATAQVLEII 238
            ....:.|....|::.|:|.....:| |::..:..|.:....::...|:          :.:.|..
Mosquito   229 TSLEDRTDELERLSQLEDEECARMD-DYIPIVYSRDELQDPMNRRHNI----------SPIPESC 282

  Fly   239 EQEEESPEQ----EAPKPALPP---------KQKQQRPVPPLPPPPANRVTQDQGTQPAAPQVPL 290
            ...|:...|    .:|:|.|..         |..:.:....|.|..:..:.:::...||.    .
Mosquito   283 HHHEDDERQWVPERSPEPTLAANTTRPWGDIKLDEMKEKAVLRPSRSMSIEEEELEPPAV----A 343

  Fly   291 QPLTAGDLQFLNLSLRQRSLPRS-------MKPF-----KDAHDISFTFNELDTSAEPEVATGAA 343
            |.|...:....|||....|..|.       ::|.     |:| |::....|.....:.:...||:
Mosquito   344 QQLHVSESAPSNLSSHSNSPDREERRGSGRVEPMLRRTTKEA-DLTSLLQEQQKEQQQQGGGGAS 407

  Fly   344 QQESNEPISRTP-LTQISYLQKIPTLPRHFSPSGQGLATPPALGSGGMGLPS--SSSASALYAAQ 405
            |.:::.. ||.| .|:|...:....:..:.|..|.|.||    .:....:|.  .|.:.:.||..
Mosquito   408 QSQASSS-SRPPWTTEIIVPEDDAVVDDYDSDGGGGTAT----ATRRRPIPQFMQSKSPSPYADG 467

  Fly   406 AAAGILPTSPL--------PLQRHQQYLPPHHQQHPGAGMGPGP-----GSGAAAGPPLGPQYSP 457
            |:.......||        ||      :||.:...|   ..|.|     ||...:.|..|...|.
Mosquito   468 ASVHGYERPPLADISNRLVPL------VPPPYPSRP---RSPTPYDEPAGSSRESTPSSGSSSSS 523

  Fly   458 GCSANPKYSNAQLPP------------PPHH------HHQLSPALSTPSPPSLLHHPAGGTSSAS 504
            ..|::..:..|.|..            .||.      ...:|.:.| |||..     ||.....|
Mosquito   524 STSSSSSFHRASLEKISNGFVSRARSISPHRAAGREGRRSVSSSRS-PSPTR-----AGDLRLGS 582

  Fly   505 AHAPF----------------------LGGPHMDMQRQSHSDDDSGCALEEYTWVPPGLRPDQVR 547
            ::||.                      |....:|....:..|.:.....::...|.| .|....|
Mosquito   583 SNAPSARAVTPADGNDVGGGAGRLLSPLAAALVDADAGAEGDTEGENGEQQLLSVAP-RRRGSGR 646

  Fly   548 LYFSQIP-DDKVPYVNSPGEQYRVR-QLLHQLPPHDNEVRYCHSLTDEERKELRLFSTQRKRDAL 610
            ...|..| ....|    ||.:|:.| ::...|.|.|.:..:..|.|:
Mosquito   647 SKASASPGSSPAP----PGRRYKERKRVARSLTPIDYDQTFMDSFTE------------------ 689

  Fly   611 GRGNVRQLMSARPCDGCDDLISTGDIAVF-ATRLGPNASWHPACFACSVCRELLVDLIYFHRD-- 672
                  |.:|..|.: .:|.|::.|...| ...|...|..:||.....|..:.......||.:
Mosquito   690 ------QHLSVTPSE-LEDYINSMDAISFEPPPLVKPAYLYPAALPSLVLTDEQGTDAQFHDEMS 747

  Fly   673 GRMYCGRHHAE---TLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGK 734
            .:.:.|:.||.   ||..|.|.|:.|                              :::...:..
Mosquito   748 AKSFYGQSHAHEGVTLNHRVSYCEWI------------------------------KKFPDNQTS 782

  Fly   735 PYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIY 799
            ...|..||:...|....|.:|:.|:                          .|..|.||:
Mosquito   783 HLALEDFDSDDEEVEQICRQAVEVE--------------------------ALFPAALPQ----- 816

  Fly   800 CSIACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPHP-------QAPLPARIPS-----SHASSSP 852
                 |.|..|.||........|.|..|.......|       ..|.|..:.|     |..||.|
Mosquito   817 -----SAGNTPQPSKPLTPATTTAPAQPGDERNEFPVHRTPAYATPSPVSLVSDLSDLSSPSSQP 876

  Fly   853 PMSPQQQQQHQATFNQAMYQMQSQQMEAAGGLVDQSKSYAASDSDAGVVKDLEHGGHMGGGDLTD 917
            | ||                               |.|.|...|..
Mosquito   877 P-SP-------------------------------SLSLATQPSPT------------------- 890

  Fly   918 FSGGRASSTSQNLSPL-------NSPGDFQPHFLPKPMELQRDGVYNFNEMSSNLDAAWS-AKPT 974
                 .||:....|||       |:|   :.||.|.|.: ..|...:.:.:||:|.:..| |.|.
Mosquito   891 -----VSSSLALGSPLLNSYHNHNAP---KHHFTPIPSD-SHDTHDSSSPLSSSLHSPQSPAAPP 946

  Fly   975 NSYHLQRQLLENPHTASMPELAGKLVAP--PAHMQHLSQLHAVSSHQFQQHEYADI------LHP 1031
            :..|         ||.:.| |...|..|  |:....:|.|...:|.:....|...:      ...
Mosquito   947 SPQH---------HTTTAP-LRPSLTVPVVPSRTPSVSPLPLDASPEELVFEIGHLDGLIFEAKS 1001

  Fly  1032 PPPPPGEIPELPTPNLSVASTALPPELMGSPTHSAGDRSLNTPMSTQSASHAP--PHPVSILSGA 1094
            ..|.|...|....|       .|.|:.:.....:.|...|..|  ::|.|.||  |||....||.
Mosquito  1002 REPTPSRAPSRSEP-------LLRPDELAFDIGNMGGLILGPP--SRSVSPAPPTPHPSLESSGG 1057

  Fly  1095 SSSSPMSGEPA 1105
            :|.||:|.|.|
Mosquito  1058 ASLSPLSWESA 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	17/96 (18%)
		LIM1_Prickle	624..682	CDD:188799	12/60 (20%)
		LIM2_Prickle	687..742	CDD:188802	5/54 (9%)
		LIM3_Prickle	747..805	CDD:188804	8/57 (14%)
Lmpt	XP_061499123.1	None