Protein Alignment pk and WTIP

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: XP_011524754.1
• Gene: WTIP / 126374
• HGNCID: 20964
• Length: 472
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 104/479 - (21%)
• Similarity: 154/479 - (32%)
• Gaps: 141/479 - (29%)

  Fly   433 PGAG-MGPGPGSGAAAGPPLGPQYSPGCSANPK-----YSNAQLPPPPHHHHQLSPALSTP---S 488
            ||.| .||.||.|..|.|.|| :...| |..|:     .|..:..|    .....|.||..   |
Human    30 PGRGRRGPRPGPGDEAAPALG-RRGKG-SGGPEAGADGLSRGERGP----RRAAVPELSAQPAGS 88

  Fly   489 PPSLLHHPAGGTSSASAHA----------------------PFLGGPHMDMQRQSHSDDDS-GCA 530
            |.:.|....||....||.:                      |..|.|.:...|.|.|...| |.|
Human    89 PRASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSA 153

  Fly   531 LEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPHDNEVRYCHSLTDEER 595
            .....::|||..|...|   |..|....|:               .||          :|.....
Human   154 GAYADFLPPGACPAPAR---SPEPAGPAPF---------------PLP----------ALPLPPG 190

  Fly   596 KELRLFSTQRKRDALGRGNVRQLMSARPCDGCDDLISTGDIAVFATRLGPNAS---WHPACFACS 657
            :|....:.:|:.:||.|...|.|.:....|.....|..| :.::..:....|.   :|..||.|.
Human   191 REGGPSAAERRLEALTRELERALEARTARDYFGICIKCG-LGIYGAQQACQAMGSLYHTDCFTCD 254

  Fly   658 VCRELLVDLIYFHRDGRMYCGRHHA----ETLKPRCSACDEIILADECTEAEGRAWHMNHFACHE 718
            .|...|....:::...::||.....    :....:||.|..:|: :...:|.|:::|...|.|..
Human   255 SCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIM-EMILQALGKSYHPGCFRCSV 318

  Fly   719 CDKQLGGQRYIMR-EGKPYCLHCFDAMFAEYCDYCGEAIGVDQG--------QMSHDGQHWHATD 774
            |::.|.|..:.:. |...||:..:..:||..|..|...|...||        .|..|   :|..
Human   319 CNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRD---YHVA- 379

  Fly   775 ECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPHPQAPL 839
             |:.|.                        ..|:....:||:                     ||
Human   380 -CYHCE------------------------DPGDEARMADSN---------------------PL 398

  Fly   840 PARIP-------SSHASSSPPMSP 856
            .|.:|       ...:|..||:.|
Human   399 AASLPCMEQLSLGCRSSCVPPLPP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	21/95 (22%)
		LIM1_Prickle	624..682	CDD:188799	12/60 (20%)
		LIM2_Prickle	687..742	CDD:188802	15/55 (27%)
		LIM3_Prickle	747..805	CDD:188804	10/65 (15%)
WTIP	XP_011524754.1	LIM1_Ajuba_like	225..278	CDD:188738	11/53 (21%)
		LIM2_Ajuba_like	290..342	CDD:188741	15/52 (29%)
		LIM	350..404	CDD:295319	16/103 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810