Protein Alignment pk and atxn7l1

DIOPT Version :10

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: XP_002933154.2
• Gene: atxn7l1 / 100498036
• XenbaseID: XB-GENE-1011002
• Length: 850
• Species: Xenopus tropicalis
• Alignment Length: 751
• Identity: 147/751 - (19%)
• Similarity: 224/751 - (29%)
• Gaps: 248/751 - (33%)

  Fly   701 CTEA-EGRAWHMNHFACHECDKQLGGQRYIMREGKPYC-------LHCFDAMFAEYCDYCG---- 753
            |..| ||:.......|....|:::......:  |||:.       |||.|....|.....|
 Frog    16 CRSASEGKEKQQEGRAMATLDRKVPSPEAFL--GKPWSSWIDAAKLHCSDNGDLEETGKEGGKSR 78

  Fly   754 EAIGVDQGQMSHDGQHWHATDECF--SCNTCRCSLLGRAF---LPRRGAIYCSIACSKGEPPTPS 813
            |.:.:::..| |...|:...|:.:  .||.|...:..:.|   ..||....|.        |:||
 Frog    79 EVMRLNKEDM-HLFGHYPGHDDFYLVVCNVCNQVVKPQVFQSHCERRHGSMCK--------PSPS 134

  Fly   814 DSSGTGMYTTPTPPTQRVRPHPQAPLPARIPSSHASSSPPMSPQQQQQHQATFNQAMYQMQSQQM 878
            .:|.                      |:.|..||....|  .|.....:....|...::.....:
 Frog   135 PASS----------------------PSNIKPSHVQMKP--KPCMSSHNPVNSNSKPFKAPRDNL 175

  Fly   879 EAAGGLVDQSKSYAASDSDAG--------VVKDLE--------HGGHMGGGDLTDFSGGRASSTS 927
                 |...:|.:.|..|...        .|..||        .|.::....:|:.|...|||.|
 Frog   176 -----LTSNNKQHTAFSSKVSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSVTNSSTTAASSAS 235

  Fly   928 QNLSPLNSPGDFQPHFLPKPME--LQRDGVYNFNEMSSNLDAAWSAKPTNSYH---LQRQLLENP 987
               |....|.  .|..:|:..|  |...|:........|     ..|.:|..:   .:|:...|.
 Frog   236 ---SLPKQPA--VPKTVPQSPEKILNGKGIGTLERKHQN-----GTKTSNKPYKRLSEREFDPNK 290

  Fly   988 H----------------TASMPELAGKLVAPPAHMQ-------HLSQL----------HAVSSHQ 1019
            |                |.....|..:...|....|       |.::.          ||.||.:
 Frog   291 HCGVLDPETKKPCTRSLTCKTHSLNHRRAVPGRKKQFDILLAEHKARSREKEVTKDKEHAPSSRE 355

  Fly  1020 FQQHEYADILHPPPPPPGE------IPELPTPNLSVASTALPP-ELMGSPTHSAGDRSLNTPMST 1077
            ..|.:        |.|..|      :..:|.|.::..:.:.|. ..:..||.:   .|:|:..|:
 Frog   356 THQSQ--------PTPAQEQSSGVALNSVPEPKVTSPAKSRPQNSALPRPTSA---NSINSASSS 409

  Fly  1078 QSASHAPPHPVSILSG--ASSSSPMSGEPAKKKGVRFEGIPDTLPRSRSYSGN----------GA 1130
            ..::..|..|||.:.|  ||..|...||        .||:.:|......|||:          |:
 Frog   410 NHSAFVPEPPVSSVGGDLASRLSSDEGE--------VEGVEETEKLDCFYSGHHPKPLAFCSFGS 466

  Fly  1131 GTSGGGERERDRDKDKEGGGRHGHGHSSRRRRRRKSSSSSSHHRSGSGHRSHSTTRADTYAPAQP 1195
            ...|.|....||..|              |.|...:|....|..|....:......:...:|...
 Frog   467 RLMGRGYYVFDRRWD--------------RFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPVTH 517

  Fly  1196 LSSSYQGPPSVLQA---ANLVH-ESPSRQQREREREREREESEESDVCSTCSSSSSSSEDYMMMY 1256
            :|||:  |.||||.   .|.|: .||....|           ..|....|....::.:.|...:.
 Frog   518 VSSSF--PASVLQPFSNPNSVYLSSPGTNSR-----------TTSSYMVTSGMLTNMAADTNSLT 569

  Fly  1257 QLPQR-RHYGGV------------RVSYVP---------------------------NDALAYDR 1281
            ..|.. .|..|.            .||.||                           ::.|:.:|
 Frog   570 SHPNAFSHATGTLNIVDSTFKSPSAVSPVPTLTPSPSQKPSKTKPSKSSKIKDLSSRSEELSGNR 634

  Fly  1282 KRKP------------------SELGGDKDKNCIIS 1299
            |:||                  |...|...|||:::
 Frog   635 KKKPQTTSSSTSSSLPLQTSSTSSFSGSHKKNCVLN 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799
		LIM2_Prickle	687..742	CDD:188802	12/48 (25%)
		LIM3_Prickle	747..805	CDD:188804	14/66 (21%)
atxn7l1	XP_002933154.2	SCA7	278..339	CDD:462422	8/60 (13%)