Protein Alignment pk and LIMS4

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: NP_001358269.1
• Gene: LIMS4 / 100288695
• HGNCID: 39941
• Length: 398
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 72/299 - (24%)
• Similarity: 101/299 - (33%)
• Gaps: 110/299 - (36%)

  Fly   561 VNSPGEQYRVR-----QLLHQLPP---HDNEVR-YC-HSLTDEERKELRLFSTQRKRDALGRGNV 615
            |||.||.|..:     |...|.|.   ::.|.| || |..
Human    86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDF------------------------- 125

  Fly   616 RQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVD--------------- 665
             |::.|..|..|      |:..:.......|.||||.||.|.:|:|:|.|
Human   126 -QMLFAPCCHQC------GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183

  Fly   666 -------------------------LIY----FHRD-------------------GRMYCGRHHA 682
                                     ||:    :|.|                   |.:||...|.
Human   184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKDLTADAQELKGELYCLPCHD 248

  Fly   683 ETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAE 747
            :...|.|.||...| ......|.|:.||:.||.|.:|:|...|.|:..|:|..||...::.:|.:
Human   249 KMGVPICGACRRPI-EGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 312

  Fly   748 YCDYCGEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSL 786
            .|.:|...|..|  .:|...:.|..  .||:|:||...|
Human   313 VCFHCNRVIEGD--VVSALNKAWCV--NCFACSTCNTKL 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	14/66 (21%)
		LIM1_Prickle	624..682	CDD:188799	22/120 (18%)
		LIM2_Prickle	687..742	CDD:188802	20/54 (37%)
		LIM3_Prickle	747..805	CDD:188804	12/40 (30%)
LIMS4	NP_001358269.1	LIM1_PINCH	72..130	CDD:188717	15/69 (22%)
		LIM2_PINCH	133..184	CDD:188718	15/56 (27%)
		LIM3_PINCH	197..247	CDD:188719	7/49 (14%)
		LIM4_PINCH	253..306	CDD:188720	20/53 (38%)
		LIM5_PINCH	314..367	CDD:188721	12/38 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910