DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pk and fhl2

DIOPT Version :9

Sequence 1:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster
Sequence 2:	NP_001120233.1	Gene:	fhl2 / 100145283	XenbaseID:	XB-GENE-969632	Length:	279	Species:	Xenopus tropicalis

Alignment Length:	178	Identity:	53/178 - (29%)
Similarity:	85/178 - (47%)	Gaps:	18/178 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 CDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPR 688
            |||.|  :|..|           ..||.:||.|..|::.|||..:..:|..:.|...::.....:
Frog    49 CDGKD--LSYKD-----------RHWHESCFHCFQCKKSLVDKPFAAKDEHLICTECYSNEYSSK 100

  Fly   689 CSACDEIIL-ADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYC 752
            ||.|.:.|: .....|.:|.:||...|.|..|.:.:|.:.:|.::.:.:|:.|::..||.:|..|
Frog   101 CSECKKTIMPGTRKMEYKGNSWHETCFICSRCQQPIGTKSFIPKDNQNFCVACYEKQFAMHCVQC 165

  Fly   753 GEAIGVDQGQMSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGAIYC 800
            .:||  ..|.:::..|.||  .|||.|..|:..|.|:.|..|....||
Frog   166 KKAI--TTGGVTYRDQPWH--KECFICTGCKKPLSGQRFTSRDEFAYC 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602
		LIM1_Prickle	624..682	CDD:188799	17/57 (30%)
		LIM2_Prickle	687..742	CDD:188802	15/55 (27%)
		LIM3_Prickle	747..805	CDD:188804	19/54 (35%)
fhl2	NP_001120233.1	LIM	<5..33	CDD:413332
		LIM1_FHL2	36..97	CDD:188806	17/60 (28%)
		LIM2_FHL2	101..157	CDD:188810	15/55 (27%)
		LIM3_Fhl2	162..218	CDD:188815	19/52 (37%)
		LIM4_FHL2	221..278	CDD:188817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910