Protein Alignment pk and prickle2

DIOPT Version :9

• Sequence 1: NP_724538.1
• Gene: pk / 45343
• FlyBaseID: FBgn0003090
• Length: 1299
• Species: Drosophila melanogaster
• Sequence 2: XP_031757102.1
• Gene: prickle2 / 100126208
• XenbaseID: XB-GENE-482891
• Length: 893
• Species: Xenopus tropicalis
• Alignment Length: 897
• Identity: 315/897 - (35%)
• Similarity: 437/897 - (48%)
• Gaps: 191/897 - (21%)

  Fly   516 DMQRQSHSDDDSGCALEEYTWVPPGLRPDQVRLYFSQIPDDKVPYVNSPGEQYRVRQLLHQLPPH 580
            |.||.|.||||||||||||.|:||||:|:||..|:|.:|||||||||||||:.|::|||||||||
 Frog    75 DFQRNSTSDDDSGCALEEYAWIPPGLKPEQVHQYYSCLPDDKVPYVNSPGEKSRIKQLLHQLPPH 139

  Fly   581 DNEVRYCHSLTDEERKELRLFSTQRKRDALGRGNVRQL---MSARPCDGCDDLISTGDIAVFATR 642
            |||||||:||.:||::||:|||.||||:.|||||||..   |:...|:.|...|:.||:||||:|
 Frog   140 DNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDMAVFASR 204

  Fly   643 LGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCGRHHAETLKPRCSACDEIILADECTEAEGR 707
            .|....|||.||.|.:|.|||||||||::||::||||||||.|||||:||||||.||||||||||
 Frog   205 AGHGVCWHPQCFVCIICNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGR 269

  Fly   708 AWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDAMFAEYCDYCGEAIGVDQGQMSHDGQHWHA 772
            .|||.||.|.||:..||||||||:||:|||.:||::::|||||.|.:.||:|||||::|||||||
 Frog   270 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCNCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 334

  Fly   773 TDECFSCNTCRCSLLGRAFLPRRGAIYCSIACSKGEPPTPSDSSGTGMYTTPTPPTQRVRPHPQA 837
            |:.||.|..|:.|||||.|||::|.|:||.|||.||.|..||||.:.........::|     .|
 Frog   335 TENCFCCAHCKKSLLGRPFLPKQGQIFCSRACSVGEDPNGSDSSDSAFQNARAKESRR-----SA 394

  Fly   838 PL----------------PARIPSSHASSS-PPMSPQQQ----QQHQATFNQAMYQMQSQQMEAA 881
            .:                |..:.|:..|:. .|:|.|..    .....:.|:........::...
 Frog   395 KIGKNKGKLDDGNMNQCGPLHVASNRLSADVDPLSLQMDLLSVSSQNPSLNRDQLWRSRDELYHY 459

  Fly   882 GGLVDQSKSYAASD--SDAGVVKDLEHGGHMGGGDLTDFSGGRASSTSQNLSPLNSPGDFQPHFL 944
            |..:::|:|.:...  |...:......|  .|.|...|......::..::||.:.....|
 Frog   460 GNKIERSQSQSPLQLLSQCNIRTSYNTG--QGAGAQPDMWAKHFNNQKRSLSMMGHSESF----- 517

  Fly   945 PKPMELQRDGVYNFNEMSSNLDAAWSAKPTNSYHLQRQLLENPHTASMPELAGKLVAPPAHMQHL 1009
                  .::|..::.:.......::|....:|::..|..|.      :|:...|   .|.:.|..
 Frog   518 ------SQEGREDYYQGRVRQQESFSDASNHSFNEARSSLR------VPKFEEK---KPMNPQQC 567

  Fly  1010 SQLHAVSSHQFQQHEYADILHPPPPPPGEIPELPTPNLSVASTALP------------------- 1055
            ...|.:::.:|.:              |..|...||..|:.|.||.
 Frog   568 RSRHPINALKFTE--------------GLTPTEQTPRGSMESLALSNATGVSADGGPKRQEHLSR 618

  Fly  1056 ---PEL--------------MGSPTHSAGDRSLNTPMSTQSASH----APPHPVSILSGASSSSP 1099
               |:|              ||:...|:..||:.:..|..||..    ||.     ||..::|.
 Frog   619 FSMPDLSKDSGMNVSEKLSNMGTLNSSSQFRSVESVRSLLSAQQYQDLAPN-----LSDLANSG- 677

  Fly  1100 MSGEPAKKKGVRFEGIPDTLPRSRSYSG---------------NGAGTSGGGERERDRDKDKEGG 1149
                       ::..:|   |.||.:.|               |....:...||.|.|.:.::..
 Frog   678 -----------KYRDVP---PHSRLHHGFTFDAGMSMNELTAQNNLKLTPMSERTRRRTQARDND 728

  Fly  1150 GRHGHGHSSRRRRRRKSSSSSSHHRSGSGHRSHSTTRADTYAPAQPLSSSYQGPPSVLQAANLVH 1214
            ..:.| |..||.||.:|.::           .|..|........:||:.:.:....::|...:..
 Frog   729 QHYRH-HRQRRSRRSRSDNA-----------LHLATEQCNKIKEKPLARTREEYERLMQQRGVRD 781

  Fly  1215 ESPSRQQREREREREREESE----------------ESDVCSTCSSSS-SSSEDYMMMYQLPQRR 1262
            ......:||.....:|..|:                :.|.|||||||| |.:|.|.:...:||
 Frog   782 SMDQAVRREMYNRYQRTASDLALQNHLYDRWGQHVNDYDWCSTCSSSSESDNEGYFLGEPIPQ-- 844

  Fly  1263 HYGGVRVSYVPNDALAYDRKR------KPSELGG---------DKDKNCIIS 1299
               ..|:.||.::.|.:...:      |.|.|||         .|.||||||
 Frog   845 ---PTRLRYVTSEDLIHQYGQCSGGIPKSSTLGGRGQLHSRKRRKSKNCIIS 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	72/94 (77%)
		LIM1_Prickle	624..682	CDD:188799	34/57 (60%)
		LIM2_Prickle	687..742	CDD:188802	41/54 (76%)
		LIM3_Prickle	747..805	CDD:188804	37/57 (65%)
prickle2	XP_031757102.1	PET_Prickle	82..178	CDD:193602	72/95 (76%)
		LIM1_Prickle	186..244	CDD:188799	34/57 (60%)
		LIM2_Prickle	249..304	CDD:188802	41/54 (76%)
		LIM3_Prickle	309..367	CDD:188804	37/57 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I4502
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	511	1.000	Inparanoid score	I1284
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	1	1.000	-	-		FOG0001066
OrthoInspector	1	1.000	-	-		mtm14087
Panther	1	1.100	-	-	LDO	PTHR24211
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3342
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190