Protein Alignment MTM1 and mtm1

DIOPT Version :10

• Sequence 1: XP_047298088.1
• Gene: MTM1 / 4534
• HGNCID: 7448
• Length: 625
• Species: Homo sapiens
• Sequence 2: NP_001015828.1
• Gene: mtm1 / 548545
• XenbaseID: XB-GENE-1002030
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 618
• Identity: 476/618 - (77%)
• Similarity: 542/618 - (87%)
• Gaps: 16/618 - (2%)

Human     8 MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYI 72
            |||.||.||||:|||| |::|:..||:|.:..:.:|.||||.|||||:|||:|||.||:|||:::
 Frog     1 MASNSTPKYNSNSLEN-SLRRSPGDGMNHEQNDEIPCLPGEALITDKDVIYMCPFYGPVKGRIHV 64

Human    73 TNYRLYLRSLETLSSHWRFEVDTCLFQDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKD 137
            |||:||.:..|               .:..:...||||||:||||||||:|||||||||||||||
 Frog    65 TNYKLYFKGEE---------------MEPLISFSVPLGVIARIEKMGGASSRGENSYGLDITCKD 114

Human   138 MRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPVEEYRRQGLPN 202
            |||||||||||.|||:.:||.||:|||||:|.|.||||.|||||..:||.||:.:.|:|||||||
 Frog   115 MRNLRFALKQEVHSRKQIFEDLTKYAFPLSHGLLLFAFQNEEKFPENGWAVYDAMTEFRRQGLPN 179

Human   203 HHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQP 267
            ..||||||||.||||||||.||||||.||::||::||.||||||||||||:||||::.|:|||||
 Frog   180 GQWRITFINKNYELCDTYPPLLVVPYSASEEDLKKVAAFRSRNRIPVLSWLHPENQSAIMRCSQP 244

Human   268 LVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLD 332
            |||||||||||||:|||:||:||.|.||||||||||:|||||||||||||||:|||.||||.|||
 Frog   245 LVGMSGKRNKDDERYLDIIRDTNGQTSKLTIYDARPNVNAVANKATGGGYESEDAYPNAELVFLD 309

Human   333 IHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHC 397
            |||||||||||||:||||||||||||||||||||||||||||||||||||||||:||||||:|||
 Frog   310 IHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVASGKSSVVVHC 374

Human   398 SDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQ 462
            ||||||||||||||||||||:||:|.|||:|||||||||||||:||||||||||.||||||||||
 Frog   375 SDGWDRTAQLTSLAMLMLDSYYRTIVGFEVLVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQ 439

Human   463 FIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLINSN 527
            ||||||||||||||||||||.|||.:|||||||||||||:|||:.|:::||.|:|.||||||:|.
 Frog   440 FIDCVWQMSKQFPTAFEFNEHFLITVLDHLYSCRFGTFLYNCENIRDKEKVREKTQSLWSLISSE 504

Human   528 KEKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKR 592
            |.|:.|||||||:|||||||||||||||||||||||||||:|||||||||||||||||||:|::|
 Frog   505 KSKYTNPFYTKELNRVLYPVASMRHLELWVNYYIRWNPRIRQQQPNPVEQRYMELLALRDDYVRR 569

Human   593 LEELQLANSAKLSDPPTSPSSPSQMMPHVQTHF 625
            |||||:.||.|::...||||||||:||.|.|.|
 Frog   570 LEELQITNSPKMNSSTTSPSSPSQIMPQVHTPF 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTM1	XP_047298088.1	PH-like	51..165	CDD:473070	70/113 (62%)
		Myotub-related	184..511	CDD:461958	279/326 (86%)
mtm1	NP_001015828.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		18/31 (58%)
		PH-like	43..142	CDD:473070	70/113 (62%)
		Myotub-related	159..482	CDD:461958	276/322 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..602		16/27 (59%)