Protein Alignment MTM1 and Mtm1

DIOPT Version :10

• Sequence 1: XP_047298088.1
• Gene: MTM1 / 4534
• HGNCID: 7448
• Length: 625
• Species: Homo sapiens
• Sequence 2: NP_001013065.2
• Gene: Mtm1 / 288762
• RGDID: 1304582
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 487/618 - (78%)
• Similarity: 557/618 - (90%)
• Gaps: 15/618 - (2%)

Human     8 MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYI 72
            |||:|.|..::|.:|.||:::.|:|||.:|::::.||||||:.||||||||||||:||:|||:||
  Rat     1 MASSSASDCDAHPVERESMRKVSQDGVRQDMSKSGPRLPGESAITDKEVIYICPFSGPVKGRLYI 65

Human    73 TNYRLYLRSLETLSSHWRFEVDTCLFQDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKD 137
            ||||||||||||               |.:.|||||||||||||||||.||||||||||||||||
  Rat    66 TNYRLYLRSLET---------------DLAPILDVPLGVISRIEKMGGVTSRGENSYGLDITCKD 115

Human   138 MRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPVEEYRRQGLPN 202
            :||||||||||||||||:|::|||:|||||::||||||:|||||.||||.:|||||||||||||:
  Rat   116 LRNLRFALKQEGHSRRDIFDVLTRHAFPLAYNLPLFAFVNEEKFKVDGWAIYNPVEEYRRQGLPD 180

Human   203 HHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQP 267
            .||||:|:|:.||||||||||||||||||||||||||||||||||||||||||||:..|:|||||
  Rat   181 RHWRISFVNQRYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENRAAIMRCSQP 245

Human   268 LVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLD 332
            |||:.|||::|||:|||:|||||||.||||||||||.||||||||||||||.:|||.:|||.|||
  Rat   246 LVGVGGKRSRDDERYLDIIRETNKQTSKLTIYDARPGVNAVANKATGGGYEGEDAYPHAELSFLD 310

Human   333 IHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHC 397
            |||||||||||::|:|||||:|||:|||||||||||||||||:|||||:|||||:||.|||||||
  Rat   311 IHNIHVMRESLRRVRDIVYPHVEEAHWLSSLESTHWLEHIKLLLTGAIRVADKVASGLSSVLVHC 375

Human   398 SDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQ 462
            |||||||||||:|||||||.|||||||||||||||||||||||:||||||||||.||||||||||
  Rat   376 SDGWDRTAQLTTLAMLMLDGFYRSIEGFEILVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQ 440

Human   463 FIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLINSN 527
            ||||||||:|||||||||||.||:.||||||||||||||.|||:|||||::.|||||:|||||||
  Rat   441 FIDCVWQMTKQFPTAFEFNECFLVAILDHLYSCRFGTFLLNCEAARERQRLAERTVSVWSLINSN 505

Human   528 KEKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKR 592
            |::|.||||.:|.|||:|||.|:|||||||||||||||||:||||:|:||||.|||||||:|||:
  Rat   506 KDEFTNPFYARESNRVIYPVTSVRHLELWVNYYIRWNPRIRQQQPHPMEQRYNELLALRDDYIKK 570

Human   593 LEELQLANSAKLSDPPTSPSSPSQMMPHVQTHF 625
            |||||||...||:|..|.||..:|:.|.:||||
  Rat   571 LEELQLATPTKLTDSSTPPSGSAQIAPRMQTHF 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTM1	XP_047298088.1	PH-like	51..165	CDD:473070	86/113 (76%)
		Myotub-related	184..511	CDD:461958	282/326 (87%)
Mtm1	NP_001013065.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		17/38 (45%)
		PH-like	44..143	CDD:473070	86/113 (76%)
		Myotub-related	162..489	CDD:461958	282/326 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..603		10/23 (43%)