Protein Alignment net and ATOH8

DIOPT Version :9

• Sequence 1: NP_001259789.1
• Gene: net / 45339
• FlyBaseID: FBgn0002931
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 95/312 - (30%)
• Similarity: 141/312 - (45%)
• Gaps: 81/312 - (25%)

  Fly    58 SPDIRPK-GTDSADSK---PIALVRNKRKSSEPFKVV--GLTTPNSKSMPGPPSSASMNATGPLK 116
            :|.:.|: |||:|..:   ....|.:.||.......|  ||.||   ..|.||:..|....||..
Human    81 APAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGPGLPTP---PPPPPPAPQSQAPGGPEA 142

  Fly   117 KRIRYTSSADSAVVLTPPAIDSP--PPNSCIP--STLRLQHEIMPNPAHIYVRHPGVTTLHRSLA 177
            :..|........::..|||..:|  ||....|  ||:|      |.|.    ..||.::
Human   143 QPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVR------PAPP----TRPGESS------ 191

  Fly   178 AHPEQLEPLALVTTKKQCVDQAGPKIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDE 242
                                     ..:.|.::......:..:.::|..:.:.:||.::|
Human   192 -------------------------YSSISHVIYNNHQDSSASPRKRPGEATAASSEIKA----- 226

  Fly   243 DLNKTGLAPISRPHQHQRNYKNMTRERRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKL 307
                                  :.:.||:.|||||||||||||||:|.||:.||.|:..||||||
Human   227 ----------------------LQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKL 269

  Fly   308 SVLRVACSYILTLSRMAGEDYSADQSVPSIATCLEAVTSTIQTEGKVKRKKD 359
            ::||:||:|||:|:|:|..|||||.|..|.:.|::..|.|:|.||:.|::||
Human   270 AILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKD 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	36/50 (72%)
ATOH8	XP_011531441.1	HLH	231..282	CDD:278439	36/50 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147320
Domainoid	1	1.000	78	1.000	Domainoid score	I8806
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007208
OrthoInspector	1	1.000	-	-		oto88324
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19290
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5566
SonicParanoid	1	1.000	-	-		X5318
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.920