Protein Alignment net and TAL1

DIOPT Version :10

• Sequence 1: NP_524820.2
• Gene: net / 45339
• FlyBaseID: FBgn0002931
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: XP_047285001.1
• Gene: TAL1 / 6886
• HGNCID: 11556
• Length: 390
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 82/357 - (22%)
• Similarity: 127/357 - (35%)
• Gaps: 117/357 - (32%)

  Fly    24 KDSPNSNDRDA--------------GFCSASSESEGGDDLVVEHARSGSPDIRP----------K 64
            :..|....|||              |....:|.:...:..|:|....|.|...|          |
Human    11 RSDPQLEGRDAAEASMAPPHLVLLNGVAKETSRAAAAEPPVIELGARGGPGGGPAGGGGAARDLK 75

  Fly    65 GTDSADSKPIALVRNKRKSSEPFKVVGLTTPNSKSMPGP---PSSASMNATGPLKKRIRYTSSAD 126
            |.|:|.::    .|::..::|      |..|     |||   |:.||:.|..|...|:
Human    76 GRDAATAE----ARHRVPTTE------LCRP-----PGPAPAPAPASVTAELPGDGRM------- 118

  Fly   127 SAVVLTPPAIDSP--PPNSCI-------------------PSTLRLQHEIMPNPAHIYVRH---P 167
              |.|:|||:.:|  |..:.:                   |...|:.....|.....|...   |
Human   119 --VQLSPPALAAPAAPGRALLYSLSQPLASLGRSGARGQGPGAGRVGRATTPTGVSFYTSAAACP 181

  Fly   168 GVTTLHRSLAAHPEQ--LEPLALVTTKKQCVDQAGPKIEAFSALLIGKQPSAKKTLKERTQKEST 230
            |    .|:..|..|:  |.|:||       ..|||.....|.      :|.|........:.:..
Human   182 G----GRAGGAQGEEVVLNPVAL-------EPQAGAPDGFFG------EPDAFPMFTTNNRVKRR 229

  Fly   231 SSSFLEASLSDEDLNKTGLAPISRPHQHQRNYKNMTR-ERRIEANARERTRVHTISAAYETLRQA 294
            .|.: |..::|            .||         |: .|||..|:|||.|...::.|:..||:.
Human   230 PSPY-EMEITD------------GPH---------TKVVRRIFTNSRERWRQQNVNGAFAELRKL 272

  Fly   295 VPAYASTQKLSKLSVLRVACSYILTLSRMAGE 326
            :|.:...:||||..:||:|..||..|:::..:
Human   273 IPTHPPDKKLSKNEILRLAMKYINFLAKLLND 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_524820.2	bHLH_TS_ATOH8	262..329	CDD:381427	23/66 (35%)
TAL1	XP_047285001.1	bHLH_TS_TAL1	244..308	CDD:381549	22/61 (36%)