DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment net and NEUROD4

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_067014.2	Gene:	NEUROD4 / 58158	HGNCID:	13802	Length:	331	Species:	Homo sapiens

Alignment Length:	147	Identity:	48/147 - (32%)
Similarity:	73/147 - (49%)	Gaps:	19/147 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 AKKTLKERTQKEST---SSSFLEASLS---DEDLNKTGLAPISRPHQHQRNYKNMT-------RE 268
            ::..:||...:..|   .||..|...|   :|:..:.|    .:|.:.....|.||       |.
Human    27 SQNEVKEEESRPGTYGMLSSLTEEHDSIEEEEEEEEDG----EKPKRRGPKKKKMTKARLERFRA 87

  Fly   269 RRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSRM--AGEDYSAD 331
            ||::||||||||:|.::.|.:.||:.:|.|:.||||||:..||:|.:||..||.:  .|:.....
Human    88 RRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGK 152

  Fly   332 QSVPSIATCLEAVTSTI 348
            ..|..:...|...||.:
Human   153 GFVEMLCKGLSQPTSNL 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	27/50 (54%)
NEUROD4	NP_067014.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..80		13/56 (23%)
		HLH	88..144	CDD:238036	29/55 (53%)
		Neuro_bHLH	146..264	CDD:289310	5/24 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..265
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810