DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment net and atoh1b

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001122151.1	Gene:	atoh1b / 493915	ZFINID:	ZDB-GENE-041201-1	Length:	206	Species:	Danio rerio

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	85/196 - (43%)	Gaps:	55/196 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 SLAAHPE--QLEPLALVTTKKQCVDQAGPK----IEAFSALLIGKQPSAKKTLKERTQKESTSSS 233
            |::.||.  :.:|.|.:|:       |.|:    :|.::                ||..:|....
Zfish    20 SISEHPRLTRSDPRAWMTS-------AAPEYSSAVENYA----------------RTAADSPMEK 61

  Fly   234 FLEASLSDEDLNKTG-------LAPISRPHQHQRNYKNMTRERRIEANARERTRVHTISAAYETL 291
            ::.:..:..:.:..|       .|.:|.|.:|          ||:.||||||.|:|.::.|::.|
Zfish    62 YISSPQAASEDHHAGSKARPGSKASVSGPQRH----------RRVAANARERRRMHGLNRAFDKL 116

  Fly   292 RQAVPAYASTQKLSKLSVLRVACSYILTLSRM------AGEDYSADQSVPSIATCLEAVTSTIQT 350
            |..:|:..:.:||||...|::|..||..||.:      :|...|...::|   ..::|.:....|
Zfish   117 RSVIPSLENEKKLSKYDTLQMAQIYITELSELLEGVVQSGAPGSQRTAIP---YAIDATSGNFAT 178

  Fly   351 E 351
            |
Zfish   179 E 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	22/50 (44%)
atoh1b	NP_001122151.1	HLH	92..150	CDD:238036	25/67 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910