Protein Alignment net and NEUROD2

DIOPT Version :9

• Sequence 1: NP_001259789.1
• Gene: net / 45339
• FlyBaseID: FBgn0002931
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 64/238 - (26%)
• Similarity: 90/238 - (37%)
• Gaps: 77/238 - (32%)

  Fly   137 DSPPPNSCIPSTLRLQHEIMPNPAHIYVRHPGVTTLHRSLAAHPEQLEPLALVTTKKQCVDQAGP 201
            |:|||               |.||      ||......:.||.|..|.
Human    35 DAPPP---------------PPPA------PGPGAPGPARAAKPVPLR----------------- 61

  Fly   202 KIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGL--APISRPHQHQRNYKN 264
                      |::.:      |.|..|......|.....:|:..:.||  |...||.:.....:.
Human    62 ----------GEEGT------EATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRK 110

  Fly   265 MTRE-------RRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSR 322
            ||:.       ||.:||||||.|:|.::||.:.||:.||.|:.||||||:..||:|.:||..||.
Human   111 MTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSE 175

  Fly   323 MAGEDYSAD-----------QSVPS---IATCLEAVTSTIQTE 351
            :.......|           .|.|:   :|.||:..:....||
Human   176 ILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTE 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	28/50 (56%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		30/147 (20%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	37/91 (41%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		1/5 (20%)
		Neuro_bHLH	180..310	CDD:403655	8/39 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810