DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment net and NEUROD1

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_002491.3	Gene:	NEUROD1 / 4760	HGNCID:	7762	Length:	356	Species:	Homo sapiens

Alignment Length:	161	Identity:	49/161 - (30%)
Similarity:	74/161 - (45%)	Gaps:	40/161 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 GKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPHQHQRNYKNMTRE-------R 269
            |::....:.|:|..::|.          .|:|         .:|.:.....|.||:.       |
Human    57 GEEEDEDEDLEEEEEEEE----------EDDD---------QKPKRRGPKKKKMTKARLERFKLR 102

  Fly   270 RIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSRMAGEDYSAD--- 331
            |::||||||.|:|.::||.:.||:.||.|:.||||||:..||:|.:||..||.:.....|.|
Human   103 RMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVS 167

  Fly   332 --------QSVPS---IATCLEAVTSTIQTE 351
                    .|.|:   :|.||:....|...|
Human   168 FVQTLCKGLSQPTTNLVAGCLQLNPRTFLPE 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	28/50 (56%)
NEUROD1	NP_002491.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..94		10/55 (18%)
		bHLH_TS_NeuroD1	75..160	CDD:381562	36/93 (39%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		2/5 (40%)
		Neuro_bHLH	160..284	CDD:403655	9/39 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810