DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment net and neurod1

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_571053.1	Gene:	neurod1 / 30169	ZFINID:	ZDB-GENE-990415-172	Length:	350	Species:	Danio rerio

Alignment Length:	185	Identity:	56/185 - (30%)
Similarity:	84/185 - (45%)	Gaps:	41/185 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 ALLIGKQPSAKKTLK--ERTQKESTSSSFLEASLSD-EDLNKTGLAPI----------------- 252
            ::::..|.|:..|.|  ..:|.|.......|..|:| ||.:..||..:
Zfish     9 SMMLESQSSSNWTDKCHSSSQDERDVDKTSEPMLNDMEDDDDAGLNRLEDEDDEEEEEEEEDGDD 73

  Fly   253 SRPHQHQRNYKNMTRE-------RRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVL 310
            ::|.:.....|.||:.       ||::||||||.|:|.::.|.|:||:.||.|:.||||||:..|
Zfish    74 TKPKRRGPKKKKMTKARMQRFKMRRMKANARERNRMHGLNDALESLRKVVPCYSKTQKLSKIETL 138

  Fly   311 RVACSYILTLSRMAGEDYSAD-----------QSVPS---IATCLEAVTSTIQTE 351
            |:|.:||..||.:.....|.|           .|.|:   :|.||:....|...|
Zfish   139 RLAKNYIWALSEILRSGKSPDLMSFVQALCKGLSQPTTNLVAGCLQLNPRTFLPE 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	28/50 (56%)
neurod1	NP_571053.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91		17/81 (21%)
		Nuclear localization signal. /evidence=ECO:0000255	82..88		2/5 (40%)
		HLH	95..153	CDD:238036	30/57 (53%)
		Neuro_bHLH	155..277	CDD:289310	9/39 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810