DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment net and Ascl2

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_113691.1	Gene:	Ascl2 / 24209	RGDID:	2159	Length:	260	Species:	Rattus norvegicus

Alignment Length:	200	Identity:	53/200 - (26%)
Similarity:	83/200 - (41%)	Gaps:	47/200 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 AIDSPPPNSCIPSTLRLQHEIMPNPAHI-YVRHPGVTTLHRSLAAHPEQLEPLALVTTKKQCVDQ 198
            |.|:.|..|| .|.|....|    .|:: :..|| |...|.|..|.    :|:|........:..
  Rat    16 ASDACPRESC-SSALPEARE----GANVHFPPHP-VPREHFSCGAP----KPVAGAPALNASLMD 70

  Fly   199 AG--PKIEAFSALLIG-----KQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPH 256
            .|  |::...|:.:.|     ::|.:.:.|:...::.|.::   |||.|.        |.::|
  Rat    71 GGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRRRSGAT---EASSSS--------AAVAR-- 122

  Fly   257 QHQRNYKNMTRERRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLS 321
                            .|.|||.||..::..::.|||.||...:.:||||:..||.|..||..|.
  Rat   123 ----------------RNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQ 171

  Fly   322 RMAGE 326
            |:..|
  Rat   172 RLLAE 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	20/50 (40%)
Ascl2	NP_113691.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	85..126		11/69 (16%)
		HLH	134..176	CDD:197674	16/41 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..239
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910