DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment net and Neurod2

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_035025.3	Gene:	Neurod2 / 18013	MGIID:	107755	Length:	383	Species:	Mus musculus

Alignment Length:	173	Identity:	54/173 - (31%)
Similarity:	79/173 - (45%)	Gaps:	24/173 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 GPKIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPHQHQRNYKN 264
            ||...|....|.|.:...:.||.|..::........|....:|.|::   |...||.:.....:.
Mouse    50 GPARAAKPVSLRGGEEIPEPTLAEVKEEGELGGEEEEEEEEEEGLDE---AEGERPKKRGPKKRK 111

  Fly   265 MTRE-------RRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSR 322
            ||:.       ||.:||||||.|:|.::||.:.||:.||.|:.||||||:..||:|.:||..||.
Mouse   112 MTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSE 176

  Fly   323 MAGEDYSAD-----------QSVPS---IATCLEAVTSTIQTE 351
            :.......|           .|.|:   :|.||:..:....||
Mouse   177 ILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTE 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	28/50 (56%)
Neurod2	NP_035025.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..130		20/82 (24%)
		bHLH_TS_NeuroD2	89..181	CDD:381563	37/94 (39%)
		Nuclear localization signal. /evidence=ECO:0000255	108..114		1/5 (20%)
		Neuro_bHLH	181..311	CDD:372170	8/39 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810