DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment net and Neurod1

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_035024.1	Gene:	Neurod1 / 18012	MGIID:	1339708	Length:	357	Species:	Mus musculus

Alignment Length:	176	Identity:	53/176 - (30%)
Similarity:	83/176 - (47%)	Gaps:	35/176 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 DQAGPKIEAFSALLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLAPISRPHQHQRN 261
            |:...::||.:|    ::.|.:...:|..:.|.     ||....:|:..:.     .:|.:....
Mouse    37 DKKEDELEAMNA----EEDSLRNGGEEEEEDED-----LEEEEEEEEEEED-----QKPKRRGPK 87

  Fly   262 YKNMTRE-------RRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILT 319
            .|.||:.       ||::||||||.|:|.::||.:.||:.||.|:.||||||:..||:|.:||..
Mouse    88 KKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWA 152

  Fly   320 LSRMAGEDYSAD-----------QSVPS---IATCLEAVTSTIQTE 351
            ||.:.....|.|           .|.|:   :|.||:....|...|
Mouse   153 LSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPE 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	28/50 (56%)
Neurod1	NP_035024.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..94		14/70 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	87..93		2/5 (40%)
		HLH	100..158	CDD:238036	30/57 (53%)
		Neuro_bHLH	160..284	CDD:289310	9/39 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810