DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment net and AgaP_AGAP009983

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_319121.4	Gene:	AgaP_AGAP009983 / 1279405	VectorBaseID:	AGAP009983	Length:	380	Species:	Anopheles gambiae

Alignment Length:	421	Identity:	185/421 - (43%)
Similarity:	228/421 - (54%)	Gaps:	107/421 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ANTNTEKLYMQLSASELSAIIMKDSPNSN--DRDAGFCSASSESEGGDDL--VVEHARSG--SPD 60
            |.:...|:|.:|||.|||||:||.:..|.  :||:||.|.|||.|  |||  :.:.:|.|  ||:
Mosquito     5 AMSTLAKMYPKLSAVELSAILMKGAAMSASLERDSGFNSGSSEHE--DDLKSLDQSSRDGLISPE 67

  Fly    61 IRPKGTDSADSKPIA---------------LVRNKRKSSEPFKVVGLTTPNSKSMPGPPSSASMN 110
                 ..|.||.|.|               ||:|||||:||.:||                |...
Mosquito    68 -----NSSEDSVPEAKLSSTGVVVTAQASSLVKNKRKSTEPLRVV----------------AETE 111

  Fly   111 ATGPLKKRIRYTSS---ADSAVVLTPPAIDSPPPNSC----------IPSTLRLQ-----HEI-- 155
            ...|||||||:...   .|::         ||.| ||          .||.:.|:     |.:
Mosquito   112 LLAPLKKRIRFDDERKHLDTS---------SPAP-SCRTASSPFRPWAPSAMTLEGGPISHPVPF 166

  Fly   156 ---MPNPAHIYVRHPGVTTLHRSLAAHP-EQLEPLALVTTKKQCVDQAGPKIEAFSALL------ 210
               .||||.:.||||.||||||:::..| |||:|||||..|......:........|.|
Mosquito   167 ASPFPNPADLLVRHPAVTTLHRAVSIKPLEQLQPLALVAKKSSASSSSSTSSSNQHAHLHHSHAS 231

  Fly   211 ---IGKQPSAKKTL----KERTQKESTSSS----FLEASLSDEDLNKTGLAPISRPHQHQRNYKN 264
               :..||.|..:|    ...|..|||.:|    ...:|.|...:::|            |||||
Mosquito   232 SGPLFVQPRAPPSLDGTNDSITDHESTVASGGHGGKSSSGSGGAISQT------------RNYKN 284

  Fly   265 MTRERRIEANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYILTLSRMAGEDYS 329
            |||||||||||||||||||||||||.||:|:|||::.|||||||:||:|||||||||||||||||
Mosquito   285 MTRERRIEANARERTRVHTISAAYEKLRRAIPAYSNAQKLSKLSILRIACSYILTLSRMAGEDYS 349

  Fly   330 ADQSVPSIATCLEAVTSTIQTEGKVKRKKDE 360
            .|.|.||||.|:|.||.|||||||:::||||
Mosquito   350 EDGSEPSIAECVEMVTKTIQTEGKIRKKKDE 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	42/50 (84%)
AgaP_AGAP009983	XP_319121.4	HLH	289..340	CDD:278439	42/50 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I14100
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H43753
Inparanoid	1	1.050	230	1.000	Inparanoid score	I5832
OMA	1	1.010	-	-		QHG26504
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007208
OrthoInspector	1	1.000	-	-		oto105674
Panther	1	1.100	-	-	LDO	PTHR19290
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5318
TreeFam	1	0.960	-	-
	12	11.930