DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment net and Neurog2

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_033848.1	Gene:	Neurog2 / 11924	MGIID:	109619	Length:	263	Species:	Mus musculus

Alignment Length:	182	Identity:	51/182 - (28%)
Similarity:	75/182 - (41%)	Gaps:	56/182 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 LLIGKQPSAKKTLKERTQKESTSSSFLEASLSDEDLNKTGLA---------------PIS----- 253
            :|:|....|..||      ...|||..|.  .||:|.:.|.|               |.|
Mouse    18 MLLGSASPASATL------TPMSSSADEE--EDEELRRPGSARGQRGAEAGQGVQGSPASGAGGC 74

  Fly   254 RP-------HQHQR----------------NYKNMTRERRIEANARERTRVHTISAAYETLRQAV 295
            ||       |:.:|                ..:.:.:.||::||.|||.|:|.::||.:.||:.:
Mouse    75 RPGRLLGLMHECKRRPSRSRAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVL 139

  Fly   296 PAYASTQKLSKLSVLRVACSYILTLS---RMAGEDYSADQSVPSIATCLEAV 344
            |.:....||:|:..||.|.:||..|:   |:|  |:.|.......|...|||
Mouse   140 PTFPEDAKLTKIETLRFAHNYIWALTETLRLA--DHCAGAGGLQGALFTEAV 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	22/50 (44%)
Neurog2	NP_033848.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..76		15/63 (24%)
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	25/69 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..253
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810