DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment net and neurod2

DIOPT Version :9

Sequence 1:	NP_001259789.1	Gene:	net / 45339	FlyBaseID:	FBgn0002931	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_571157.1	Gene:	neurod2 / 114435	ZFINID:	ZDB-GENE-010608-3	Length:	363	Species:	Danio rerio

Alignment Length:	199	Identity:	57/199 - (28%)
Similarity:	88/199 - (44%)	Gaps:	33/199 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 EPLALVTTKK--QCVDQAG-----PKIEAFSALLIGKQPSAKKTLK---ERTQKESTSSSFLEAS 238
            ||..|...:|  ..||.:|     .|.|......:|.:...:.::|   .|.|.|.......:..
Zfish     8 EPSLLPDMQKFGGWVDDSGSEDSKTKDEEQERCRLGDEDLDEGSVKGGGSRAQSEIAGEEDYDED 72

  Fly   239 LSDEDLNKTGLAPISRPHQHQRNYKNMT-------RERRIEANARERTRVHTISAAYETLRQAVP 296
            :.::|..:.|..  .||.:.....:.||       :.||.:||||||||:|.:::|.:.|.:.||
Zfish    73 VDEDDCGEEGDG--DRPKKRGPKKRKMTPARLERSKVRRQKANARERTRMHDLNSALDNLLKVVP 135

  Fly   297 AYASTQKLSKLSVLRVACSYILTLSRMAGEDYSAD-----------QSVPS---IATCLEAVTST 347
            .|:.||||||:..||:|.:||..||.:.......|           .|.|:   :|.||:..:..
Zfish   136 CYSKTQKLSKIETLRLAKNYIWALSEILRNGKRPDVVSYVQTLCKGLSQPTTNLVAGCLQLNSRN 200

  Fly   348 IQTE 351
            ..||
Zfish   201 FLTE 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
net	NP_001259789.1	HLH	269..320	CDD:278439	27/50 (54%)
neurod2	NP_571157.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..116		25/109 (23%)
		Nuclear localization signal. /evidence=ECO:0000255	93..99		1/5 (20%)
		HLH	105..164	CDD:238036	29/58 (50%)
		Neuro_bHLH	166..285	CDD:289310	8/39 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810