DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment net and ascl1

DIOPT Version :9

Sequence 1:NP_001259789.1 Gene:net / 45339 FlyBaseID:FBgn0002931 Length:360 Species:Drosophila melanogaster
Sequence 2:XP_002944648.3 Gene:ascl1 / 100490701 XenbaseID:XB-GENE-1032967 Length:199 Species:Xenopus tropicalis


Alignment Length:162 Identity:36/162 - (22%)
Similarity:67/162 - (41%) Gaps:53/162 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 ESTSSSFLEASLSDEDLNKTGLAP-----------------ISRPHQHQRNYKN----MTRERRI 271
            ::::::.:|::||.:...:..|.|                 .::|.|.:|...:    |..:||:
 Frog     2 DNSAANIMESNLSGQQQQQHFLQPACFFPQNVQLSPAEEHEAAKPKQIKRQRSSSPELMRCKRRL 66

  Fly   272 ------------------EANARERTRVHTISAAYETLRQAVPAYASTQKLSKLSVLRVACSYIL 318
                              ..|.|||.||..::..:.|||:.||..|:.:|:||:..||.|..||.
 Frog    67 NFTGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIR 131

  Fly   319 TLSRMAGEDYSADQSVPSIATCLEAVTSTIQT 350
            .|.::..|.              :||::..|:
 Frog   132 ALQQLLDEH--------------DAVSAAFQS 149

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
netNP_001259789.1 HLH 269..320 CDD:278439 22/68 (32%)
ascl1XP_002944648.3 bHLH_TS_ASCL1_Mash1 78..148 CDD:381585 24/83 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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