DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment na and F17C8.6

DIOPT Version :9

Sequence 1:	NP_001096981.2	Gene:	na / 45338	FlyBaseID:	FBgn0002917	Length:	2233	Species:	Drosophila melanogaster
Sequence 2:	NP_497974.1	Gene:	F17C8.6 / 175626	WormBaseID:	WBGene00008911	Length:	279	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	121/215 - (56%)
Similarity:	148/215 - (68%)	Gaps:	19/215 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  1782 MENFSLFYSNEEDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLLKGRLECDPQKDRLL 1846
            ||||||.||:|||||||||||||||..||:|||.|:..||||||||:|||||||||.:.:.|.||
Worm     1 MENFSLLYSSEEDALLSYADIRNFQLVWNMVDIEQKRSIPVRRVKFLLRLLKGRLEVNDESDGLL 65

  Fly  1847 FKYMCYELDKLHNGEDVTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWL 1911
            ||:||:|:::||||:||:||||:||||||||||||:|||||||.|||.||::||||||.|||.||
Worm    66 FKHMCHEMERLHNGDDVSFHDVLNMLSYRSVDIRKSLQLEELLQREELEYIIEEEVAKHTIRAWL 130

  Fly  1912 EGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPT 1976
            |.|||.|:|    ||.|:|  |..::.......|..||            :.| .|.|.....|.
Worm   131 ENCLKNIKA----KQNNTL--GKMSSIGSTFAFPQSQE------------VLT-KGVVLTEASPE 176

  Fly  1977 SDAFSPTFSSTENEEKDGSS 1996
            .|:......|.:.:.:.|:|
Worm   177 EDSLQGDKGSGKKKAQRGNS 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
na	NP_001096981.2	Ion_trans	373..654	CDD:278921
		Ion_trans	734..927	CDD:278921
		Ion_trans	1240..1497	CDD:278921
		Ion_trans	1571..1793	CDD:278921	8/10 (80%)
F17C8.6	NP_497974.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158341
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16416at33208
OrthoFinder	1	1.000	-	-		FOG0004135
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.800