Protein Alignment sens and ZAP1

DIOPT Version :10

• Sequence 1: NP_524818.1
• Gene: sens / 45328
• FlyBaseID: FBgn0002573
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_012479.1
• Gene: ZAP1 / 853390
• SGDID: S000003592
• Length: 880
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 108/480 - (22%)
• Similarity: 175/480 - (36%)
• Gaps: 127/480 - (26%)

  Fly   120 NNENSKQDYQEQDEDMPLNLSTKERITSDDSNRDQYHSSSNNSSRSSSSSEVEQLH--------P 176
            ||||..|       .|.|.||:..|.    :.::..:.|:||::.::|:......|        |
Yeast   420 NNENGNQ-------TMNLLLSSINRC----NPKNNLNGSNNNTAGATSTDHQHHHHRIQFHSHKP 473

  Fly   177 MTSLNVTPPPLSAVNLKSSSTPQQ-----------QRQRSQGNIIWSPASMCERSARREQYGLKM 230
            ..:..|....:||.|..:..|...           :|.|:|......|....:....|..:..|.
Yeast   474 NRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPTKD 538

  Fly   231 EEQGDEEEHQVDPIVRKFKYERRTASISSLQSPISSLSAPASNAVQDLEFEVAQQQLYAHRSAFM 295
            .|..|                     .|||:..:.|..:|.......:.|....::
Yeast   539 LESTD---------------------FSSLEDSLPSSISPPIQTTSTINFNWCFKE--------- 573

  Fly   296 AGLTGNNLELLTQHLKLK-SEQPQQ-----QQQQHRIKDEQQQDNR------------------S 336
               ..||      .||.| .|.|:.     ..|:|.:||...||.:                  .
Yeast   574 ---EKNN------DLKCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDD 629

  Fly   337 AAALMNLVAAAEFGYMRNQHQQPQ-------QQQQQQLHHQQQPQQHQHQQQH--PDST-ATDVA 391
            ..:::|.:..........|...|.       .:::..|.|...||.|:..:..  ||.| |.||:
Yeast   630 TCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCPNPQTHEVSKADGAPDMTSANDVS 694

  Fly   392 ------------------RRSSSSSSYQGENEE----KRSGRNFQC--KQCGKSFKRSSTLSTHL 432
                              .:|.||:....::.|    .|....:||  ..|.::|.:...|..||
Yeast   695 NIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHL 759

  Fly   433 LIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCLKAFSQSSNLITHMRKHTGYKPF 497
            .:||..:||.|:.|.:.|..:..:.:||..|:||||:||.:|.|.|:.||:|..|:|.|||.||.
Yeast   760 KVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPL 824

  Fly   498 GCHLCDQSFQRKVDLRRHRESRHEE 522
            .|.:|.:.|....:|.:|.::..::
Yeast   825 QCKICGKRFNESSNLSKHIKTHQKK 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sens	NP_524818.1	zf-C2H2	413..435	CDD:395048	7/23 (30%)
		C2H2 Zn finger	415..435	CDD:275368	6/21 (29%)
		zf-C2H2	441..463	CDD:395048	6/21 (29%)
		C2H2 Zn finger	443..463	CDD:275368	5/19 (26%)
		zf-H2C2_2	455..480	CDD:463886	12/24 (50%)
		C2H2 Zn finger	471..491	CDD:275368	9/19 (47%)
		zf-H2C2_2	483..506	CDD:463886	10/22 (45%)
		C2H2 Zn finger	499..516	CDD:275368	4/16 (25%)
ZAP1	NP_012479.1	COG5048	292..761	CDD:227381	74/390 (19%)
		C2H2 Zn finger	743..762	CDD:275368	5/18 (28%)
		SUF4-like	766..>814	CDD:411020	20/47 (43%)
		C2H2 Zn finger	770..795	CDD:411020	8/24 (33%)
		C2H2 Zn finger	770..790	CDD:275368	5/19 (26%)
		C2H2 Zn finger	798..818	CDD:275368	9/19 (47%)
		zf-H2C2_2	810..834	CDD:463886	10/23 (43%)
		C2H2 Zn finger	826..846	CDD:275368	5/19 (26%)