DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sens and CG14655

DIOPT Version :9

Sequence 1:NP_524818.1 Gene:sens / 45328 FlyBaseID:FBgn0002573 Length:541 Species:Drosophila melanogaster
Sequence 2:NP_649494.1 Gene:CG14655 / 40594 FlyBaseID:FBgn0037275 Length:525 Species:Drosophila melanogaster


Alignment Length:436 Identity:98/436 - (22%)
Similarity:163/436 - (37%) Gaps:107/436 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   177 MTSLNVTPPPLSAVNLKSSSTPQQQRQRSQGNIIWSPASMCERSARREQY-GLK----------- 229
            |.|.:|..|..:..:..|....||:..::....:..|.:.|     :|.: ||.           
  Fly     1 MCSTSVLCPLCAVPSFGSIDALQQRLIKAANGPLACPFANC-----KELFLGLDKLTIHLFSHTS 60

  Fly   230 -MEEQGDEEEHQVDPI-VRKF-------KYERRTASISSLQSPISSLSAPASNAVQDL-EFEVAQ 284
             |.::|:|......|. .|.|       :..:||.|...:.:|....:.|.::.  |: ||..  
  Fly    61 LMAQEGNESPANGQPASSRGFLAAAPPKRRAKRTRSKPVVPTPPPVRTTPPAHC--DICEFSF-- 121

  Fly   285 QQLYAHRSAFMAGLTGNNLELLTQHLKLKSE----QPQQQQQQHRIKDEQ--------------- 330
                            .|.||...|::|..|    :|:|::.|.:..|::               
  Fly   122 ----------------RNTELRDMHVRLVHENAEGEPKQKEPQQKEPDQEPYKCHLCSKTFRMKG 170

  Fly   331 ----------------------QQDNRSAAALMNLVAA------------AEFGYMRNQH----- 356
                                  ...:.:.|:..:.|.|            .|.|.:.|.:     
  Fly   171 SLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCT 235

  Fly   357 -QQPQQQQQQQLHHQQQPQQHQHQQQHPDSTATDVARRSSSSSSYQGENEEKRSGR-NFQCKQCG 419
             .||..........||.|...:.....|.....||..:|.::..:..:::...:|. .:.|:.|.
  Fly   236 ASQPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICA 300

  Fly   420 KSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCLKAFSQSSNL 484
            ::|....:...|||.||:.:|:.|..||:.|.:.|.:..|..||:||||.||.||.|.|.|..:.
  Fly   301 RTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSF 365

  Fly   485 ITHMRKHTGYKPFGCHLCDQSFQRKVDLRRHRESRHEEAPPVEDLK 530
            :.|.|.|||..|:.|.||.::|:.||..|.||....|...|.:.:|
  Fly   366 LVHTRIHTGVMPYKCELCQKTFRYKVSQRTHRCPTEEAQTPEQLIK 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sensNP_524818.1 zf-C2H2 413..435 CDD:278523 6/21 (29%)
C2H2 Zn finger 415..435 CDD:275368 6/19 (32%)
COG5048 423..>497 CDD:227381 30/73 (41%)
zf-H2C2_2 428..452 CDD:290200 10/23 (43%)
C2H2 Zn finger 443..463 CDD:275368 6/19 (32%)
zf-H2C2_2 455..480 CDD:290200 13/24 (54%)
C2H2 Zn finger 471..491 CDD:275368 8/19 (42%)
C2H2 Zn finger 499..516 CDD:275368 7/16 (44%)
CG14655NP_649494.1 C2H2 Zn finger 268..288 CDD:275368 3/19 (16%)
zf-H2C2_2 281..304 CDD:290200 3/22 (14%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
zf-H2C2_2 339..361 CDD:290200 13/21 (62%)
C2H2 Zn finger 352..372 CDD:275368 8/19 (42%)
zf-H2C2_2 364..389 CDD:290200 10/24 (42%)
C2H2 Zn finger 380..396 CDD:275368 7/15 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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