DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sens and CG12391

DIOPT Version :9

Sequence 1:	NP_524818.1	Gene:	sens / 45328	FlyBaseID:	FBgn0002573	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_610639.1	Gene:	CG12391 / 36170	FlyBaseID:	FBgn0033581	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	94/464 - (20%)
Similarity:	174/464 - (37%)	Gaps:	100/464 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 GQRDRDFALTPEKEHELQMNNNNENSKQDYQEQD----------EDMPLNLSTKERITSDDSNRD 153
            |::|.|    .||:......:||:::::|..|.|          ||........|.|..|:...|
  Fly   127 GEKDTD----KEKKATHLHEDNNDDAEKDGDEADAEDEDDVEKPEDEDGTEEGDEAIEEDEDALD 187

  Fly   154 QYHSSSNNSSRSSSSSEVEQLHPMTSLNVTPPPLSAVNLKSSSTPQQQRQRSQGNIIW--SPASM 216
            :         ....:.|||::.|              :.::.:.       ::|.:|.  .|..:
  Fly   188 E---------DEDPNEEVEEIEP--------------DFETGTD-------AEGELITGDEPGDL 222

  Fly   217 CERSARREQYGLKMEEQGDEEEHQV----DPIVRKFKYERRTASISSLQSPISSLSAPASNAVQD 277
            .:...|..    |.||..||::.:|    :.:|..||.:     |.:  :|...|.....| |..
  Fly   223 ADVPIRER----KKEEPVDEDQCRVCTSKEELVCLFKKQ-----IDA--TPADMLLVICPN-VSI 275

  Fly   278 LEFEVAQQQLYAHRSAFMAGLT-----GNNLELLTQHLKLKSEQPQQQQQQHR------------ 325
            |..:...|.:.   :..|..||     ...||...|.|:.:..:.:.:.::.|
  Fly   276 LPKDFMPQFIC---TKCMGSLTIAIQLRKQLETTDQELRKRLSRSKNKVRRPRGYVVIDAPVTDS 337

  Fly   326 IKDEQQQDNRSAAALMNLVAAAEFGYMRNQHQQPQQQQQQQLHHQQQPQQHQHQQQHPDSTATDV 390
            .:||.:.|:....:.:....:|:.....:...:.:         :::|......::.|....||.
  Fly   338 SEDEDELDDEFKVSDVAGTTSADSDSADSDDSEKE---------KKKPGPRGRPRKKPLKRGTDS 393

  Fly   391 ARRSSSSSSYQGENEEKRSGRNFQCKQCGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSD 455
            ....||:...:.:.....|...|:|..|..:|.|..:...|...| :...:.|..|||:|..:..
  Fly   394 DGEPSSAQKKKYQPSSTASVGPFECPNCDLTFSRKQSYVLHRKTH-ERIEHACPICGKKFKVEWA 457

  Fly   456 MKKHTYIHTGEKPH-KCTVCLKAFSQSSNLITHM-RKHT--GYKPFGCHLCDQSFQRKVDLRRHR 516
            .|.|...|..|:.| :|.:|.|.|...:.|..|| ::|.  |: .:.|..|.::|..:..|:||:
  Fly   458 YKTHMQRHEQERAHFRCELCPKIFRLRAELKHHMAQRHDEHGF-IYECKRCQRTFLTQQRLQRHQ 521

  Fly   517 E---SRHEE 522
            .   .||:|
  Fly   522 AVGCQRHKE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sens	NP_524818.1	zf-C2H2	413..435	CDD:278523	6/21 (29%)
		C2H2 Zn finger	415..435	CDD:275368	5/19 (26%)
		COG5048	423..>497	CDD:227381	22/77 (29%)
		zf-H2C2_2	428..452	CDD:290200	7/23 (30%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		zf-H2C2_2	455..480	CDD:290200	9/25 (36%)
		C2H2 Zn finger	471..491	CDD:275368	7/20 (35%)
		C2H2 Zn finger	499..516	CDD:275368	5/16 (31%)
CG12391	NP_610639.1	zf-AD	240..313	CDD:285071	18/83 (22%)
		zf-C2H2	416..438	CDD:278523	6/21 (29%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		zf-C2H2	443..465	CDD:278523	7/21 (33%)
		C2H2 Zn finger	445..465	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..491	CDD:275368	5/16 (31%)
		C2H2 Zn finger	504..521	CDD:275368	5/16 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100