Protein Alignment sens and sens-2

DIOPT Version :10

• Sequence 1: NP_524818.1
• Gene: sens / 45328
• FlyBaseID: FBgn0002573
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_723223.1
• Gene: sens-2 / 33957
• FlyBaseID: FBgn0051632
• Length: 746
• Species: Drosophila melanogaster
• Alignment Length: 625
• Identity: 197/625 - (31%)
• Similarity: 257/625 - (41%)
• Gaps: 172/625 - (27%)

  Fly     5 SPPPSPHSQQPS--PAGLGCHGAALDKQWMQRASAFNTVIASAAAQKLNGRDLPFLYNPLLYSSA 67
            :|.|:|:..||.  ||....|..|       ..|||..|:    .:|.|..|....::    .|.
  Fly   114 NPNPNPNHPQPQMPPASTSPHEYA-------PMSAFKAVL----PKKRNSDDASLAFS----ISR 163

  Fly    68 LLWPQFLLSSATALGTPLTPMTPKSPASVVLGQRDRDFALTPEKEHELQMNNNNENSKQDYQEQ- 131
            |:..:.|.:.|.|:|  |.|.||                 ..:..:.:.|.:.|:...|.:.:|
  Fly   164 LVKTEQLTAMAAAVG--LKPPTP-----------------LEDNNNSISMLSKNQQMHQQHHQQS 209

  Fly   132 ---DEDMPLNLSTKERITSDDSNRDQYHSSSNNSSRSSSSSEVE-----------QLHPMT---- 178
               ....|..:|..|::      |.|..|.|.:.|||..||:::           .||..:
  Fly   210 HLAQRPKPAFISASEKL------RRQSRSRSRSRSRSPCSSQIDMEDADSNHSHRSLHSRSRSRS 268

  Fly   179 -----SLNVTPPPLSAVNLKSSSTPQQQRQRSQGNIIWSPASMCE------------RSARREQY 226
                 |.:.:....|:|.|:..|.|...|..|...   :.||..|            .|.:.:.:
  Fly   269 RSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSG---ASASASELLITANGGGRSIGSKKSDLF 330

  Fly   227 GLKMEEQGDEEEHQVDPIVRKFKYERRT--------ASISSLQSPISSLSAPASNAVQDLEFEVA 283
            .:....:.||...|           |||        .:.|.|..|.:.|.|.......:.:..:.
  Fly   331 SVSALLRRDEPPPQ-----------RRTPRSPPLGHLTSSGLAMPFNPLEAMRQGYPPNYDAAMF 384

  Fly   284 QQQLYAHRSAFMAGLTGNNLELLTQHLKLKSEQPQQQQQQHRI-------KDEQQ---------- 331
            |:.|::....|.|.:..:           :.:|.||||||.:.       .|.|:
  Fly   385 QRPLFSPALPFFAAVAFH-----------QGQQQQQQQQQQQSGLAAGYHPDSQENLFRLRSLMV 438

  Fly   332 ------QDNRSAAALMNLVAAAEFGY---------MRNQH-QQPQQQQQQQLHHQ--QQPQQHQH 378
                  |:|.||||.....|||..|.         ....| ..|........||.  :.|..||.
  Fly   439 PLQSAGQNNSSAAAAAAAAAAAAVGVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQF 503

  Fly   379 QQQH-----------PDSTATDVARRSSSSSSYQGENEEKRSGRN---------------FQCKQ 417
            ...:           |........|.......|..|...|..|..               |:|||
  Fly   504 SDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQ 568

  Fly   418 CGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCLKAFSQSS 482
            |||.||||||||||||||||||||||.|||||||||||||||||||||||||||.||.|||||||
  Fly   569 CGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSS 633

  Fly   483 NLITHMRKHTGYKPFGCHLCDQSFQRKVDLRRHRESRHEE 522
            |||||.|||||||||.|.||.::||||||||||:|::|.:
  Fly   634 NLITHSRKHTGYKPFSCKLCHKAFQRKVDLRRHKETQHTD 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sens	NP_524818.1	zf-C2H2	413..435	CDD:395048	19/21 (90%)
		C2H2 Zn finger	415..435	CDD:275368	18/19 (95%)
		zf-C2H2	441..463	CDD:395048	20/21 (95%)
		C2H2 Zn finger	443..463	CDD:275368	18/19 (95%)
		zf-H2C2_2	455..480	CDD:463886	22/24 (92%)
		C2H2 Zn finger	471..491	CDD:275368	16/19 (84%)
		zf-H2C2_2	483..506	CDD:463886	17/22 (77%)
		C2H2 Zn finger	499..516	CDD:275368	12/16 (75%)
sens-2	NP_723223.1	COG5048	<504..672	CDD:227381	99/167 (59%)
		C2H2 Zn finger	509..530	CDD:275368	2/20 (10%)
		SUF4-like	534..>589	CDD:411020	26/54 (48%)
		C2H2 Zn finger	538..558	CDD:411020	3/19 (16%)
		C2H2 Zn finger	538..558	CDD:275368	3/19 (16%)
		C2H2 Zn finger	566..586	CDD:411020	18/19 (95%)
		C2H2 Zn finger	566..586	CDD:275368	18/19 (95%)
		C2H2 Zn finger	594..614	CDD:275368	18/19 (95%)
		zf-H2C2_2	606..631	CDD:463886	22/24 (92%)
		C2H2 Zn finger	622..642	CDD:275368	16/19 (84%)
		C2H2 Zn finger	650..677	CDD:275368	15/24 (63%)