DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sens and B0310.2

DIOPT Version :9

Sequence 1:	NP_524818.1	Gene:	sens / 45328	FlyBaseID:	FBgn0002573	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_508109.1	Gene:	B0310.2 / 180403	WormBaseID:	WBGene00015138	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	79/350 - (22%)
Similarity:	123/350 - (35%)	Gaps:	95/350 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NSSRSSSSSEVE----QLHPMTSLNVTPPPLSAVNLKSSSTPQQQRQRSQGNIIWSPASMCERSA 221
            ||..||.|.::|    ::..|.:..|:||..|                |..::...|      |.
Worm   102 NSLCSSKSLDLEPIEIKVEAMENPVVSPPIFS----------------SDDSVKGMP------SR 144

  Fly   222 RREQYGLKMEEQGDEEEHQVDPIVRKFKYERRTASISSLQSPISSLSAPASNAVQDLEFEVAQQQ 286
            :|.:..|:...|...:|:.|.|......:     .:..:..||     |.|||       ...|:
Worm   145 KRAKRSLEDTVQMLSKENSVSPPPPSLPF-----VLPQIPVPI-----PFSNA-------ALMQR 192

  Fly   287 LYAH---RSAFMAGLTGNNLELLTQHLKLKSEQPQQQQQQHRIKDEQQQDNRSAAALMNLVAAAE 348
            ...|   ..|:        |..:.||      ||..:..:.:.           ||||.:...|.
Worm   193 WLGHPLTNPAY--------LNAMFQH------QPAPKPSEEQF-----------AALMKITMHAA 232

  Fly   349 FGYMRNQHQQPQQQQQQQLHHQQQPQQHQHQQQHPDSTATDVARRSSSSSSYQGENEEKRSGRNF 413
             .:|:...|.|...     |..:...:........|....:|:...|:....:.|:....:|...
Worm   233 -NFMKTVPQLPVSN-----HFTESDAEDIKIDVESDEGEIEVSPSPSTGDITENESSSSSTGPMI 291

  Fly   414 QCKQCGKSFKRSSTLSTHLLIHSDTRPYPCQY--CGKRFHQKSDMKKHTYIHTGEKPHKCTVCLK 476
            . ..||..   ...|.         :|:.|.:  |||||..|..:|||.:||||.:||.|..|.|
Worm   292 S-PNCGDG---DCALE---------KPFICMHNNCGKRFANKFLLKKHMFIHTGLRPHTCPHCHK 343

  Fly   477 AFSQSSNLITHMRKHTGYKPFGCHL 501
            .|::..||:.|.:.|:   |...||
Worm   344 KFNRKDNLLRHKKTHS---PTSAHL 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sens	NP_524818.1	zf-C2H2	413..435	CDD:278523	3/21 (14%)
		C2H2 Zn finger	415..435	CDD:275368	3/19 (16%)
		COG5048	423..>497	CDD:227381	26/75 (35%)
		zf-H2C2_2	428..452	CDD:290200	8/25 (32%)
		C2H2 Zn finger	443..463	CDD:275368	10/21 (48%)
		zf-H2C2_2	455..480	CDD:290200	13/24 (54%)
		C2H2 Zn finger	471..491	CDD:275368	7/19 (37%)
		C2H2 Zn finger	499..516	CDD:275368	1/2 (50%)
B0310.2	NP_508109.1	C2H2 Zn finger	308..330	CDD:275368	10/21 (48%)
		zf-H2C2_2	323..347	CDD:290200	13/23 (57%)
		C2H2 Zn finger	338..358	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I4014
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050