Protein Alignment lin and Lins1

DIOPT Version :9

• Sequence 1: NP_524815.1
• Gene: lin / 45325
• FlyBaseID: FBgn0002552
• Length: 858
• Species: Drosophila melanogaster
• Sequence 2: XP_006229420.1
• Gene: Lins1 / 308704
• RGDID: 1308792
• Length: 742
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 130/694 - (18%)
• Similarity: 241/694 - (34%)
• Gaps: 222/694 - (31%)

  Fly   214 YLREWPTNKLLQFLSNL--QLLFDIYLKQNAKGFI------------CTR-------IMDVCDAL 257
            |:.|.....:.:.|.:|  ::|....|:.:..|:|            ||.       :.||.|.:
  Rat     3 YIVEIKMESVQEILDHLYRKVLLGATLEDDLHGYIVYLNPDLSEQAVCTASSVARSDVRDVLDGM 67

  Fly   258 IRNDHKLIDEIIVLAGYENSYVQFLAGRVLAAFLVIAKQELNDEWLQKIVD------QLFNFEQL 316
             ...|.:   .|:....|.|..|...||  |..:.:.:..|.|..|.:::.      ....:.:|
  Rat    68 -AGQHGV---SILPEAQECSRRQLQTGR--AWEVTLLQLTLIDMVLSRVLSAETESRAKAGYREL 126

  Fly   317 DQAAVQKIHFSLDIIKRIVEWKDMEIHPLDDDWMASANSTSAASSVVPLSTEASVSYMHFPVQEQ 381
            .:..:|.|.....:| |:::                 ||....|.   |:.:...|.::|.::|:
  Rat   127 TEVLLQSIELDSKLI-RVLQ-----------------NSDKLLSY---LAAKCLASLLYFQLREK 170

  Fly   382 PLATNYFALQFREDTEGERETGQEAPDNRDRHRRHFGEDMNVAYEPHPAPQSTTMPSGCHVVTLT 446
            .:.:|.:.                                                :.|......
  Rat   171 KMLSNSWV------------------------------------------------TFCQKHLSD 187

  Fly   447 DSESFDTTHLKCITIQKLEHKWPTLVKNMSELMAPTHQDAAE----------------------- 488
            .||..:..|..|:           |...|.|:....|...||
  Rat   188 SSEGGEAVHCLCV-----------LAAVMKEIFKDAHSQRAESLKQLLTPFDNTFEAFYNSLFSQ 241

  Fly   489 ------------HCVLNFLQLWENIISVKANLSID--ETRPYYAQLDKFELL-------LSHSLS 532
                        ..::.||:|.|.:::.:.:|.:.  ..|..:.:....::|       :...|.
  Rat   242 HFGNFKNPSNIISSLMCFLELLELLVASRIHLKLHLRSQRMLFLKPHALDILAWPIPAFIKRKLV 306

  Fly   533 CTVYKQMLCLFNEALCYGS--TLALQD-MLPEETCKLAHQIV--CHVRGFRILESLPRRQPDNMV 592
            ..:.|.:||...|..|..|  ||...| :|..:...||..::  .|:..::.| ::|
  Rat   307 ILIKKCLLCKVGEDFCRESVPTLMSPDHLLDSDMLALADALLHAIHLGLWKAL-TVP-------- 362

  Fly   593 SLIGYNGKPMVYANGTITLAHAAQSGDSEEDGAPLDLIEMDKTLLQKMVLLVLKSIAVTVKEIRS 657
                  |||..:            .||..:.|..| ....|...|:...|:.:||:.:..:...|
  Rat   363 ------GKPSCF------------GGDEVQPGCRL-RAGPDHVTLRAASLITVKSLEIKFQNCTS 408

  Fly   658 DSSDSSIDSTDYDAFQDMMLIERSIRDVLSKLETFIKQTLEFHPECHFSKILIHLFDDQDDHLIE 722
             :::...|            :::.:.:.|:.|:..::.:|:.|..|.:   |..:|.:|||.::|
  Rat   409 -ATEMKAD------------LQKFLPEFLAFLKPQLQPSLQLHNPCEW---LSRVFIEQDDDMLE 457

  Fly   723 AMVCTLDV----TSGISFRNNAFPELVAML--------NPVYTFLEFLKMTSNSSDLLLDLLVSN 775
            |...:|.:    |.......:..||..|.:        ||...||.|||..:..|.:|||.|:|:
  Rat   458 AAKASLSIYLHLTREWDTSTSLTPEKEAWIHSTHGHGYNPHCIFLFFLKNIAFDSTVLLDFLISS 522

  Fly   776 ETCFLLYLLRLLKYIRMNWTMFVHSCHTFGMGSAMLDEAMGVLI 819
            |||||.|.::.||.::.:|..|:.:|..|    |.::...||.:
  Rat   523 ETCFLEYFVKYLKLLQKDWGHFLSTCQFF----AAMESQCGVSV 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lin	NP_524815.1	LINES_N	442..801	CDD:291366	87/419 (21%)
		LINES_C	814..849	CDD:291367	2/6 (33%)
Lins1	XP_006229420.1	LINES_N	201..548	CDD:405394	83/390 (21%)
		LINES_C	701..737	CDD:405395

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16057
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.030