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Protein Alignment trol and dsd

DIOPT Version :9

Sequence 1:	NP_001027038.3	Gene:	trol / 45320	FlyBaseID:	FBgn0284408	Length:	4479	Species:	Drosophila melanogaster
Sequence 2:	NP_001263013.1	Gene:	dsd / 43315	FlyBaseID:	FBgn0039528	Length:	1323	Species:	Drosophila melanogaster

Alignment Length:	1339	Identity:	259/1339 - (19%)
Similarity:	384/1339 - (28%)	Gaps:	473/1339 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1029 NCTF----CREDAYLCNTGECVADNQRCNGIADCADGSDERHC------ARIYCPPNKLACNGTC 1083
            |||.    |:.|      |:|..|.| |.    ||||.....|      .|:|.|...:......
  Fly    52 NCTAHGGRCQND------GQCQEDGQ-CL----CADGWQGPECQFCGGKVRMYHPMGTIHDGWGN 105

  Fly  1084 VSRRIKCDGIRDCLDGYDEMYCPETN---NHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLEC 1145
            .|..:||..:.|...       |..|   |..|::..|:              |.|..:.|. ||
  Fly   106 YSVSVKCSWLIDARH-------PHWNRRHNTNPSRTANI--------------RIHLREFAT-EC 148

  Fly  1146 IDSSLQCNEIKDCSDGSDEELSVCF------GTATTRLKP-----SDCSPEQFYCDE----SCYN 1195
            ....|...:    .|..|..|...|      |..:.|..|     |..:...|:.|:    |.:|
  Fly   149 GWDHLYIYD----GDSVDSPLLAVFSGLMYRGNFSIRRVPQVIATSGTALVHFFSDDAYNMSGFN 209

  Fly  1196 RSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCD---RHRHCEDGSDEANC------ 1251
            .:.:.|   .|...||||.||   ...:|..|.|.     ||   |...|...:...||
  Fly   210 LTYKMN---SCPSDSDEVECS---GHGKCRDGDCI-----CDPMYRGEACNIAACPNNCFESKNQ 263

  Fly  1252 --CYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQC---------- 1304
              |..:|.||:   |..|.|.    .:||..|..   |......|......:|..
  Fly   264 GHCRLDQERCS---CYEGFAG----DDCSQISAH---GAWSTVHPKHSPAPAGSASHGATIWRDT 318

  Fly  1305 -------------VSSSVRCNGRT-------DCQDSSDEQNCAAD-------------------S 1330
                         :.|:...||..       |..:..|::..|:.                   |
  Fly   319 LHIVGGESYGRGKLMSTYDFNGNVWETVHPEDGSEVPDKRYGASTVMYGDKIFMYGGVVKGHGIS 383

  Fly  1331 NDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGG--------------RPLPP 1381
            |:.....::.:|:.:..:                 ||....:..||              ..|.|
  Fly   384 NELWAFDVSARTWANISV-----------------RADPSCNATGGTTAMCGPLHVVGHTATLVP 431

  Fly  1382 GFTDRNGRLEI-------PNI----------------RVEDAGTYVCEAVGYASYIPGQQVTVNL 1423
            |:.|:|....:       ||.                |:.....||.:. ||     |.....:.
  Fly   432 GYGDKNNYQYMVVIFGHSPNYGYLNTVQEFNFASREWRIVPTTGYVVKG-GY-----GHSAAYDF 490

  Fly  1424 NVER---YNDVGSRPE--------------------------SACTEYQATCMNGECIDKSSICD 1459
            ..|:   |..:.|..|                          ||...:.|..:|...:   .:..
  Fly   491 LTEKVYVYGGIVSESESSQVLSSRLYAYEPATRVWSLLSAAPSARLLHTANFVNQGLM---MVFG 552

  Fly  1460 GNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRY 1524
            ||     ..::.|.|.|.||.....:..:..|                 |.....|.|.......
  Fly   553 GN-----THNDTSQSYGAKCYSQDLLVYDVYC-----------------DSWHYHPMPGHLQADL 595

  Fly  1525 NEFQCRSGHC---------IPKSFQCDNVPD--------CTDGTDEVGCMAPLPIRPPPQSVSLL 1572
            ..|    ||.         |...|....:.|        |:..|.:..|.|   .||..:.:
  Fly   596 ARF----GHSSVVFEESLYIYGGFNGQLLNDMLRYQPGYCSYYTKQEKCTA---ARPGVKCI--- 650

  Fly  1573 EYEVLELTCVA-TGTPTPTIVWRLNWGHVPDKCESKS-YGGTGTL-----RCPDMRPQD---SGA 1627
             ::|.::.|:| |......|..|..:.:|  .|.||| ...|..|     ||.::....   |.|
  Fly   651 -WDVQKMRCIAITQVQRSAIYGREQYDYV--ACPSKSRLTLTSELLHDVHRCQELASCQSCVSTA 712

  Fly  1628 YSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTY 1692
            :.|       |:..|            .||          ..|.|.:...........|..:...
  Fly   713 FGC-------TYCGN------------GVC----------SKERCRETTSMASVFFESSTQMAVS 748

  Fly  1693 AIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMG 1757
            ...||:.:..:.|..:|  .:.:::      .:...||..:..:.|          ||...|...
  Fly   749 TASPPLNAKHLDSCPIS--EEYLVS------SVCDQLHNCRACSAN----------LACRWDSEH 795

  Fly  1758 NQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDG 1822
            |:.|||       .:|  .|..:|                 |||.      .:...|......:.
  Fly   796 NRCKSY-------TSY--GGLALN-----------------RTQD------EVACSPSCASLTNC 828

  Fly  1823 RKASREEIMMILANVDNILIRLGYLDS----TAREVDLINIALDSAGTADKGL--GSASLVEKCQ 1881
            :..:.:|.:. ..|....:.|..|..|    ..||.........||......|  ||.:.:...|
  Fly   829 QNCTEDECIW-CQNEQRCVDRNAYTASFPYGQCREWTTFTAKCRSAPIQSTALAVGSTTALSSAQ 892

  Fly  1882 CPPGYVGDSCESC----ASGYVRQPGGPWLGHCV------PFIPDSCPSGTYGDPRRGVPCKECP 1936
            |  ||. :||:.|    |.|:........||.||      |:....|....:    ....|..|.
  Fly   893 C--GYY-NSCQMCLDDPACGWCDNGSNTGLGRCVVGGALAPYDDTECALKHW----FFTSCPRCN 950

  Fly  1937 CPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGT 2001
            |......|....|:|.        ||...||..||:|..||.|||: .||.|:|   ..||..|.
  Fly   951 CNGHSYCNDQQHCEQP--------CNNLTTGAHCEKCRTGYWGNPI-NGGKCQR---CDCNGQGV 1003

  Fly  2002 YSVHSNGTCQC-KDSVIGEQCDTCKSKS-FHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTST 2064
            |.....|.|.| ...::|:.|:.|.|:: :|                 |.....|.:|...:...
  Fly  1004 YCHPDTGKCFCTTKGIVGDHCEKCDSQNHYH-----------------GDPLKGSCYYELTIDYQ 1051

  Fly  2065 F---------------------GRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQS 2108
            |                     |:..:|..|.:..:.  |....:.|..|..|:.|..:|   .:
  Fly  1052 FTFNLSKKEDRHFTQINFRNSPGKPEIDADFTITCSV--PAKMDISVKRAGSPDMLILVG---VN 1111

  Fly  2109 GNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMS 2147
            .:|.....|             |..|...:||..|..::
  Fly  1112 CSTFRHRFP-------------KTDYQFGHSPDDNSSLT 1137

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.